MRI: Acquisition of a single-crystal diffractometer for the University of Minnesota

MRI：为明尼苏达大学购买一台单晶衍射仪

基本信息

批准号：
1229400
负责人：
John Ellis
金额：
$ 25.59万
依托单位：
University of Minnesota-Twin Cities
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-15 至 2015-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1229400&HistoricalAwards=false
关键词：
MRI Acquisition single crystal diffractometer

项目摘要

With this award from the Major Research Instrumentation Program that is co-funded by the Chemistry Research Instrumentation and Facilities (CRIF) Program, Professor John Ellis from University of Minnesota-Twin Cities and colleagues Lawrence Que, William Tolman, Calvin Sun and Connie Lu will acquire a single crystal diffractometer with a compact copper radiation source, photon detector and a top-of-the-line cryostat capable of collecting high-resolution diffraction data on very small specimens. The proposal is aimed at enhancing research training and education at all levels, especially in areas such as (a) hydrocarbon-stabilized metal-atom reagents; (b) electron-transfer molecular catalysts; (c) bioinorganic studies of metallo-copper enzymes and synthesis of sustainable polymeric materials; (d) study and optimization of the physico-mechanical properties of drugs; (e) model complexes of non-heme iron metalloenzymes; (f) design of biologically active agents; (g) synthetic routes to biologically active compounds; (h) Pro-Leu-Gly-NH2 and dopamine receptor modulation study and anthrax toxin lethal factor inhibition; and (i) study of parthenolide and helenalin analogues.An X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here will impact a number of areas, including organic and inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research not only at the University of Minnesota but also at neighboring colleges and universities in the Twin Cities area.

通过从化学研究工具和设施（CRIF）计划共同资助的主要研究仪器计划的奖项，明尼苏达州 - 彼此大学的约翰·埃利斯（John Ellis）教授及其同事劳伦斯·奎克（Lawrence Que），威廉·托尔曼（William Tolman），卡尔文·桑（William Tolman），卡尔文·孙和康妮·卢（Connie Lu非常小样品的衍射数据。该提案旨在增强各个级别的研究培训和教育，尤其是在（a）碳氢化合物的金属原子试剂等领域；（b）电子转移分子催化剂；（c）金属铜酶的生物无机研究和可持续聚合物材料的合成；（d）研究和优化药物的物理机械特性；（e）非血红素金属酶的模型复合物；（f）生物活性剂的设计；（g）生物活性化合物的合成路线；（h）亲欧 - 吉利-NH2和多巴胺受体调节研究和炭疽毒素致死因子抑制；（i）研究对par苯甲甲基和海伦素类似物的研究。X射线衍射仪可以准确，精确地测量分子的整个三维结构，包括键距离和角度，并提供有关分子相对于邻近分子的分子空间排列的准确信息。此处描述的研究将影响许多领域，包括有机和无机化学，材料化学和生物化学。该乐器将不仅在明尼苏达大学，而且在双城地区的邻近学院和大学不仅是教学的组成部分。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Reductive Disproportionation of CO 2 Mediated by Bimetallic Nickelate(-I)/Group 13 Complexes: Reductive Disproportionation of CO 2 Mediated by Bimetallic Nickelate(-I)/Group 13 Complexes

双金属镍酸盐(-I)/第13族配合物介导的CO 2 还原歧化: 双金属镍酸盐(-I)/第13族配合物介导的CO 2 还原歧化

DOI：
10.1002/ejic.201801452
发表时间：
2019
期刊：
European Journal of Inorganic Chemistry
影响因子：
2.3
作者：
Vollmer, Matthew V.;Cammarota, Ryan C.;Lu, Connie C.
通讯作者：
Lu, Connie C.

Bimetallic nickel-lutetium complexes: tuning the properties and catalytic hydrogenation activity of the Ni site by varying the Lu coordination environment

双金属镍镥配合物：通过改变Lu配位环境来调节Ni位点的性能和催化加氢活性

DOI：
10.1039/c8sc04712j
发表时间：
2019
期刊：
Chemical Science
影响因子：
8.4
作者：
Ramirez, Bianca L.;Sharma, Prachi;Eisenhart, Reed J.;Gagliardi, Laura;Lu, Connie C.
通讯作者：
Lu, Connie C.