RAPID/MRI: Acquisition of a Triple-Quad Mass Spectrometer for Quantitative Identification of Dispersants and Water-Soluble Oil in the Gulf of Mexico

RAPID/MRI：购买三重四极杆质谱仪，用于定量鉴定墨西哥湾的分散剂和水溶性油

• 批准号: 1058448
• 负责人: Elizabeth Kujawinski
• 金额: $ 20万
• 依托单位: Woods Hole Oceanographic Institution
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1058448&HistoricalAwards=false
• 关键词: RAPID; MRI; Acquisition; Triple; Quad

The PI's request MRI RAPID funding to acquire a triple-quad Mass Spectrometer for quantitative identification of dispersants and water-soluble oil in the Gulf of Mexico. Dispersants were applied to the leak at the bottom of the ocean. Preliminary results using the PI's Fourier-transform ion cyclotron resonance (FT) mass spectrometer show that is possible identify the active ingredient of this dispersant in samples collected during research cruises in the Gulf of Mexico. Components of the dispersant have even been found in samples taken from within the underwater oil plume deep below the ocean's surface (~1100 m). Now the PI's would like to quantify this compound in order to assess its environmental fate in this environment. In order to quantify these marker compounds, a mass spectrometer designed for sensitive and accurate quantification of targeted compounds is required. The PI's have identified a triple-quadrupole mass spectrometer (triple-Q-MS) as the most appropriate instrument for their needs. With the help of the EPA, the PI's now have the appropriate method ready and have been running samples on a triple-Q-MS in a colleague's lab. The increased sensitivity and quantitative accuracy of the triple-Q-MS will allow them to quantify dispersant components and other target compounds at lower concentrations, thus providing important constraints on modeling and predictive efforts underway in other research groups. Broader Impacts This research has the potential to provided unprecedented data on the environmental fate of both petroleum and dispersant components as they interact with the extant biological, chemical, and physical processes of the Gulf of Mexico. Beyond the immediate needs of the Gulf oil spill the development of the methods described in the proposal will have broad applications not only in oil spill research but also in marine organic matter characterization and its interactions with biological, chemical and physical processes. The instrument will be available for Gulf oil spill related research in a timeframe consistent with the intent of the RAPID funding mechanism.

PI要求MRI快速资金获得三分之二的质谱仪，以定量鉴定墨西哥湾的分散剂和水溶油。将分散剂应用于海洋底部的泄漏。使用PI的傅立叶转变离子回旋共振（FT）质谱仪的初步结果表明，在墨西哥湾研究过程中收集的样品中，可以确定该分散剂的活性成分。在海洋表面以下深处（〜1100 m）的水下油羽流中，甚至发现了分散剂的成分。现在，PI想量化这种化合物，以评估其在这种环境中的环境命运。为了量化这些标记化合物，需要设计用于敏感和准确量化靶向化合物的质谱仪。 PI已确定三局部质谱仪（Triple-Q-MS）是满足其需求的最合适仪器。在EPA的帮助下，PI现在已经准备好了适当的方法，并且已经在同事实验室的三重Q-MS上运行样本。 Triple-Q-MS的灵敏度和定量准确性的提高将使它们能够在较低浓度下量化分散剂成分和其他目标化合物，从而在其他研究小组中对正在进行的建模和预测性工作提供重要的限制。更广泛的影响，这项研究有可能在与墨西哥湾的现有生物学，化学和物理过程相互作用时提供有关石油和分散剂成分的环境命运的前所未有的数据。除了海湾油的直接需求外，该提案中描述的方法的发展不仅在溢油研究中，而且在海洋有机物特征及其与生物，化学和物理过程的相互作用中都有广泛的应用。该仪器将在与快速融资机制的意图一致的时间范围内用于海湾漏油有关的研究。