Acquisition of a FT-ICR Mass Spectrometer for Structural Characterization of Natural Organic Matter

购买 FT-ICR 质谱仪用于天然有机物的结构表征

• 批准号: 0619608
• 负责人: Elizabeth Kujawinski
• 金额: $ 103.79万
• 依托单位: Woods Hole Oceanographic Institution
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2010-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0619608&HistoricalAwards=false
• 关键词: Acquisition; FT; ICR; Mass; Spectrometer

This proposal requests support for the acquisition of a Fourier-transform ion cyclotron resonance mass spectrometer (FT-ICR MS) for research in aquatic biogeochemistry at the Woods Hole Oceanographic Institution. The proposed instrumentation is intended to support novel research directions in organic geochemistry and marine geochemistry, including ultrahigh resolution and high mass accuracy over a broad molecular weight range, versatile ionization modes including electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and matrix-assisted laser desorption ionization (MALDI), and other options for the structural elucidation of large molecules. Applications are expected to include a broad array of projects in the general area of molecular level elucidation of the biotic and abiotic processes that govern the cycling, transformation and preservation of marine organic matter. It will be managed as a cost center at WHOI, open to faculty, postdoctoral associates and students with technical support and/or training provided, depending on user qualifications and needs. Broader ImpactsThe planned educational initiatives specifically target research by graduate students, who will have extensive access to the facility for methods analysis and research applications, undergraduates who will have access through summer institute courses and use, and minority students for whom annual fellowships will be provided to apply FT-ICR mass spectrometry to research projects. The facility itself will be an important new capability for marine researchers, accessible to both WHOI and outside users.

该提案要求支持在伍兹孔海洋学机构的水生生物地球化学研究中获取傅立叶转变离子回旋共振质谱仪（FT-ICR MS）。 The proposed instrumentation is intended to support novel research directions in organic geochemistry and marine geochemistry, including ultrahigh resolution and high mass accuracy over a broad molecular weight range, versatile ionization modes including electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) and matrix-assisted laser desorption ionization (MALDI), and other options for the structural elucidation of large分子。 预计应用程序将在分子水平阐明的一般领域中包括一系列项目，这些项目阐明了循环，转化和保存海洋有机物物质的生物和非生物过程。 它将作为WHOI的成本中心管理，向教职员工，博士后员工和学生提供技术支持和/或培训的学生，具体取决于用户资格和需求。 更广泛的影响计划的教育计划特别针对研究生的研究，他们将广泛访问方法分析和研究应用程序，本科生将通过夏季学院的课程和使用访问，并为他们提供年度奖学金的少数族裔学生，以将FT-ICR质量质谱应用于研究项目。该设施本身将成为海洋研究人员的重要新功能，Whoi和外部用户都可以访问。