Summer Undergraduate Research in Chemistry and Biochemistry at Miami University

迈阿密大学化学与生物化学暑期本科生研究

• 批准号: 1004875
• 负责人: Christopher Makaroff
• 金额: $ 28.63万
• 依托单位: Miami University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1004875&HistoricalAwards=false
• 关键词: Summer; Undergraduate; Research; Chemistry; Biochemistry

This award from the Division of Chemistry (CHE) and the Division of Biological Infrastructure (DBI) supports a Research Experience for Undergraduates (REU) site led by Christopher A. Makaroff at Miami University (Ohio) for three summers, commencing in 2010. The site will support ten students per summer in a ten week program. The research projects focus on collaborative research in interdisciplinary areas of chemistry and biology. Sample projects include: (1) the recently-discovered system that transports fully-folded proteins into the thylakoid lumen; (2) the development of polymeric columns for separations of chemical species; (3) the synthesis of biologically-active natural products; (4) the elucidation of the fate of tannin under in vivo conditions; (5) the synthesis and study of reconfigurable surfaces, responsive to light and/or chemical stimuli; (6) the study of heterocyst differentiation in cyanobacteria; (7) the study of the structure and dynamics of integral membrane proteins with NMR methods; (8) the study of proteins involved in chromosome condensation and sister chromatid cohesion during meiosis and mitosis; (9) the design and development of tools to effectively measure student learning . Besides being exposed to cutting-edge research at a research-active institution, the students participating in this program will participate in site visits, professional development activities, and ethical training. Students targeted for the recruitment to the proposed site will come from schools without significant opportunities for research as well as schools with large populations of students underrepresented in chemistry.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide practical, hands-on research training to a significant number of students who might not have this opportunity at their home institution. The interdisciplinary projects that the students will work on while at Miami University (Ohio) are excellent examples of the kinds of cross-disciplinary work that is becoming more and more typical of the most fruitful avenues for modern laboratory research. Students participating in research at this site will be well-prepared for graduate school, and eventual employment as part of the country's technical workforce.

该奖项获得了化学系（CHE）和生物基础设施（DBI）的该奖项，支持由迈阿密大学（俄亥俄州）（俄亥俄州）的克里斯托弗·A·马卡罗夫（Christopher A. 研究项目着重于化学和生物学跨学科领域的合作研究。 样本项目包括：（1）最近发现的系统，该系统将完全折叠的蛋白质运输到类囊体管腔中； （2）用于分离化学物质的聚合物柱的发展； （3）生物活性天然产物的合成； （4）在体内条件下阐明单宁的命运； （5）对光和/或化学刺激有反应的可重构表面的合成和研究； （6）研究蓝细菌中杂环分化的研究； （7）使用NMR方法研究整体膜蛋白的结构和动力学； （8）研究在减数分裂和有丝分裂过程中参与染色体凝结和姐妹染色单体内聚的蛋白质的研究； （9）工具的设计和开发，以有效地衡量学生学习。 除了在研究活性机构中接受尖端研究外，参加该计划的学生还将参加现场访问，专业发展活动和道德培训。 招募招募的学生将来自学校，而没有大量的研究机会，以及大量学生人数不足的学校。 此REU网站旨在为可能在其家庭机构没有这个机会的大量学生提供实践，动手的研究培训。 学生将在迈阿密大学（俄亥俄州）进行的跨学科项目是跨学科工作的绝佳例子，这些工作正变得越来越典型地用于现代实验室研究。 参加该网站研究的学生将为研究生院做好准备，并最终作为该国技术劳动力的一部分。