Metallacyclobutene and Vinylcarbene Reaction Chemistry

金属环丁烯和乙烯基碳烯反应化学

• 批准号: 0911765
• 负责人: Joseph O'Connor
• 金额: $ 43.8万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0911765&HistoricalAwards=false
• 关键词: Metallacyclobutene; Vinylcarbene; Reaction; Chemistry

The Inorganic, Bioinorganic and Organometallic Chemistry Program supports the efforts of Professor Joseph M. O'Connor of the University of California San Diego to investigate late-metal metallacyclobutene complexes. Such complexes have been proposed as key intermediates in a large number of important metal-mediated transformations, including alkyne polymerizations, enyne methathesis reactions, and in the synthesis of cyclopropenes, furans, pyrones, and benzannulated compounds. The development of new synthetic routes to these targets maximizes the potential for subsequent reactivity. Isolable metallacyclobutene complexes allow for: a) structural studies, b) well-defined reactivity studies, c) the development of new reactions, d) appropriate modeling of key steps in reactions which are thought to involve metallacyclobutene intermediates, and e) applications of metallacyclobutene-derived products in many areas of the chemical sciences. Undergraduate and graduate students trained in the area of organometallic chemistry are well-positioned to make important contributions to both industrial and academic endeavors which require interdisciplinary research in areas such as materials, inorganic and organic chemistry.

无机，生物有机和有机金属化学计划支持加利福尼亚大学圣地亚哥分校的约瑟夫·M·奥康纳（Joseph M. 在许多重要的金属介导的转化中，已经提出了这样的复合物为关键中间体，包括炔烃聚合，enyne甲脉反应，以及环丙烯，呋喃，猪，吡咯和苯苯克的合成中。 这些目标的新合成途径的发展最大化了随后的反应性的潜力。 可隔离的金属周期二丁烯复合物允许：a）结构研究，b）定义明确的反应性研究，c）新反应的发展，d）对反应中的关键步骤的适当建模，这些反应中的关键步骤被认为涉及金属丙酰丁烯衍生产品在化学学院许多地区的应用。 在有机金属化学领域接受培训的本科生和研究生对工业和学术努力做出重要贡献，这些贡献需要在材料，无机和有机化学等领域进行跨学科研究。