Using Physical Models to Enhance Biomolecular Education

使用物理模型加强生物分子教育

• 批准号: 0442409
• 负责人: Tim Herman
• 金额: --
• 依托单位: Milwaukee School of Engineering
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-03-15 至 2006-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0442409&HistoricalAwards=false
• 关键词: Using; Physical; Models; Enhance; Biomolecular

Physical models, based on atomic coordinates and built using rapid-prototyping technology, are being used in combination with traditional educational materials to engage students in a meaningful exploration of the three-dimensional concepts of biomolecular structure. The students' use of these models is guided by supporting materials, including:(i) the "Molecule of the Month" web site, where for the past three years, a different molecular structure from the Protein Data Bank has been featured in a series of pages with concise text and compelling illustrations; (ii) a Chime tutorial that introduces students to the use of computer visualization tools; and (iii) structure files in the Protein Data Bank that are explored with these computer tools to further investigate the structure and function of each molecular topic. The intellectual merit of this project is the demonstration of physical molecular models as kinesthetic tools that engage students in an exploration of molecular structure, especially when used along with computer imagery. The broader impacts of the project arise from the use of the models in a variety of educational settings, and the involvement of pre-service and in-service teachers as well as biology undergraduates.

基于原子坐标并使用快速推广技术构建的物理模型与传统的教育材料结合使用，以使学生对生物分子结构的三维概念进行有意义的探索。 学生对这些模型的使用是通过支持材料进行指导的，包括：（i）“本月分子”网站，在过去的三年中，与蛋白质数据库的不同分子结构在一系列具有简洁文本和引人入胜的插图的页面中介绍了蛋白质数据库； （ii）介绍学生使用计算机可视化工具的铃声教程； （iii）使用这些计算机工具探索的蛋白质数据库中的结构文件，以进一步研究每个分子主题的结构和功能。该项目的智力优点是将物理分子模型作为动力学工具的演示，这些工具吸引了学生参与分子结构的探索，尤其是与计算机图像一起使用时。 该项目的更广泛影响是由模型在各种教育环境中的使用以及服务前和服务教师以及生物学本科生的参与。