CREST3: Engaging Undergraduates in the Community of Science through Modeling

CREST3：通过建模让本科生参与科学界

基本信息

批准号：
1725940
负责人：
Tim Herman
金额：
$ 60万
依托单位：
Milwaukee School of Engineering
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-01 至 2021-06-30
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1725940&HistoricalAwards=false
关键词：
CREST3 Engaging Undergraduates Community Science

项目摘要

This project builds on recent experiences that demonstrate the power of physical models of proteins to engage students' interest in the molecular biosciences. The project will have a dual focus on undergraduate students who are currently underrepresented in the sciences and on undergraduate faculty who teach topics related to molecular structure and function. Faculty will lead small teams of students in an exploration of a current research topic, with a special emphasis on the process of scientific research. In order to enhance the students' understanding of a particular molecular process, the team will design a physical model of a protein that plays a key role in that process. In so doing, the students will be introduced to the community of science and begin to see themselves as legitimate members of that research community. At the same time, faculty in this project will collaborate in the development of hands-on instructional materials that will transform the way this topic is currently taught in their bioscience classrooms. Instructional materials will begin with current student understanding and scaffold their knowledge so that they can better understand the significance of cutting edge research. Both components of our project support current efforts to improve undergraduate education as called for by the National Science Foundation's Vision and Change report. This project will be carried out in collaboration with the undergraduate student chapters of the American Society of Biochemistry and Molecular Biology (ASBMB). The intellectual merit of this project rests on students' exploration of a topic and modeling of a protein that is related to the research of a scientist who will be honored at the annual meeting of this professional society. Students will bring their models to the annual meeting where they will have an opportunity to meet with the distinguished researcher and their colleagues in an informal "teaching session". Past experience has demonstrated that the physical models will serve as thinking tools to stimulate meaningful conversations between researchers (experts) and students (novices). In a second component of this project, undergraduate faculty will participate in a collaborative summer workshop that will focus on the development of student-centered instructional materials that can be used to enhance students' understanding of structure/function relationships. These instructional materials will include accurate physical models of proteins created by 3D printing technologies as well as schematic models of proteins involved in molecular pathways, digital animations of proteins, and molecular landscapes that place proteins within their cellular contexts. Project assessment will measure both the persistence of underrepresented minority students in their pursuit of a career in science and the impact of the program on the teaching practices of the participating faculty. The results of this project will be disseminated via workshops at future annual meeting of the ASBMB. The project's instructional materials will also be available for loan through the Milwaukee School of Engineering Model Lending Library. This project is being jointly funded by the Directorate for Biological Sciences, Division of Biological Infrastructure and the Directorate for Education and Human Resources, Division of Undergraduate Education as part of their efforts to address the challenges posed in Vision and Change in Undergraduate Biology Education: A Call to Action (http://visionandchange.org/finalreport/).

该项目基于最近的经验，这些经验证明了蛋白质物理模型的力量使学生对分子生物科学的兴趣。该项目将双重关注本科生，这些学生目前在科学和本科教师中的人数不足，他们教授与分子结构和功能有关的主题。教师将带领小组学生团队对当前的研究主题进行探索，并特别强调科学研究的过程。为了增强学生对特定分子过程的理解，团队将设计一个在该过程中起关键作用的蛋白质的物理模型。这样一来，学生将被介绍给科学社区，并开始将自己视为该研究社区的合法成员。同时，该项目的教师将在开发动手教学材料方面进行合作，这些材料将改变本主题目前在其生物科学教室中教授的方式。教学材料将从当前的学生理解和脚本脚本知识开始，以便他们可以更好地理解尖端研究的重要性。我们项目的两个组成部分都支持当前的努力，以改善国家科学基金会的愿景和变更报告所要求的。该项目将与美国生物化学和分子生物学学会（ASBMB）的本科生章节合作进行。该项目的智力优点取决于学生对主题的探索和对与科学家研究有关的蛋白质的建模，该蛋白将在这个专业社会的年度会议上受到尊重。学生将把他们的模特带到年度会议上，在那里他们将有机会在非正式的“教学课程”中与杰出的研究人员及其同事会面。过去的经验表明，物理模型将用作思维工具，以刺激研究人员（专家）和学生（新手）之间的有意义的对话。在该项目的第二个组成部分中，本科教师将参加一个合作的夏季研讨会，该研讨会将着重于以学生为中心的教学材料的开发，这些材料可用于增强学生对结构/功能关系的理解。这些教学材料将包括由3D打印技术创建的蛋白质的准确物理模型，以及涉及分子途径，蛋白质数字动画以及将蛋白质放置在细胞环境中的蛋白质的示意图。项目评估将衡量代表性不足的少数族裔学生在追求科学职业的持久性以及该计划对参与教师的教学实践的影响。该项目的结果将通过ASBMB未来年度会议的研讨会来传播。该项目的教学材料也将通过密尔沃基工程模型贷款图书馆提供贷款。该项目由生物学科学，生物基础设施部和教育和人力资源局，本科教育司共同资助，这是他们为解决本科生物学教育中挑战和变化所带来的挑战的一部分：呼吁行动呼吁（http：//////////////////////////visionandchange.org/finalreport/）。

项目成果

期刊论文数量（6）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Physical Models Support Active Learning as Effective Thinking Tools

物理模型支持主动学习作为有效的思维工具

DOI：
10.1021/bk-2019-1337.ch003
发表时间：
2019
期刊：
ACS symposium series
影响因子：
0
作者：
Terrell, Cassidy A.;Franzen, Margaret A.;Herman, Timothy;Malapati, Sunil;Newman, Dina L.;Wright, L. Kate
通讯作者：
Wright, L. Kate

Meeting report: BioMolViz workshops for developing assessments of biomolecular visual literacy

会议报告：BioMolViz 开发生物分子视觉素养评估研讨会

DOI：
10.1002/bmb.21440
发表时间：
2020
期刊：
Biochemistry and Molecular Biology Education
影响因子：
1.4
作者：
Procko, Kristen;Engelman, Shelly;Jakubowski, Henry;Beckham, Josh T.;Dean, Diane M.;Franzen, Margaret A.;Novak, Walter R. P.;Roberts, Rebecca;Roca, Alberto I.;Shor, Audrey C.
通讯作者：
Shor, Audrey C.

Building a Community of Practice for the Assessment of Biomolecular Visual Literacy

建立生物分子视觉素养评估实践社区

DOI：
10.1096/fasebj.2020.34.s1.00466
发表时间：
2020
期刊：
The FASEB Journal
影响因子：
0
作者：
Procko, Kristen;Beckham, Josh T.;Dean, Diane M.;Dries, Dan R.;Engelman, Shelly;Franzen, Margaret A.;Jakubowski, Henry;Novak, Walter R.P.;Porter, Sandra;Roberts, Rebecca
通讯作者：
Roberts, Rebecca

Game‐based activities targeting visual literacy skills to increase understanding of biomolecule structure and function concepts in undergraduate biochemistry

以视觉素养技能为目标的基于游戏的活动，以增进对本科生物化学中生物分子结构和功能概念的理解

DOI：
10.1002/bmb.21398
发表时间：
2020
期刊：
Biochemistry and Molecular Biology Education
影响因子：
1.4
作者：
Terrell, Cassidy R.;Nickodem, Kyle;Bates, Alison;Kersten, Cassandra;Mernitz, Heather
通讯作者：
Mernitz, Heather