Acquisition of a Console for a 400 MHz NMR Spectrometer

购买 400 MHz NMR 波谱仪控制台

• 批准号: 0075728
• 负责人: Kenton Whitmire
• 金额: $ 14.25万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2003-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0075728&HistoricalAwards=false
• 关键词: Acquisition; Console; 400; MHz; NMR

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at William Marsh Rice University will acquire a console for a 400 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) metallocene-alumoxane interactions; b) solution structural characterization of tri-metallic molecules; c) characterization of the product distribution and relative yield from the facile hydrogen/deuterium exchange in organic and organometallic aromatic compounds catalyzed by Group 13-mercury complexes; d) synthesis of molecules of precise length and constitution for electronic, photonic, and template self-replication applications; e) development of novel organic synthetic methods and the total synthesis of natural products; f) metal atom chemistry; g) chemistry of novel aromatic systems; h) terpene biosynthesis using recombinant microorganisms; and g) the synthesis of single-stranded DNA oligomers containing nonnatural nucleotides. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including materials chemistry and biochemistry.

凭借化学研究仪器和设施 (CRIF) 计划的这一奖项，威廉马什莱斯大学化学系将获得 400 MHz 核磁共振波谱仪的控制台。该设备将使研究人员能够开展以下方面的研究：a) 茂金属-铝氧烷相互作用； b) 三金属分子的溶液结构表征； c) 13族汞配合物催化的有机和有机金属芳族化合物中容易进行的氢/氘交换的产物分布和相对产率的表征； d) 合成具有精确长度和结构的分子，用于电子、光子和模板自我复制应用； e) 新型有机合成方法的开发和天然产物的全合成； f) 金属原子化学； g) 新型芳香系统的化学； h) 使用重组微生物进行萜烯生物合成； g) 含有非天然核苷酸的单链DNA寡聚物的合成。 核磁共振 (NMR) 光谱是化学家阐明分子结构的最强大工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于进行前沿研究的化学家来说，获得最先进的核磁共振波谱分析至关重要。这些核磁共振研究的结果将对包括材料化学和生物化学在内的许多领域产生影响。