MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance Console Upgrade for Chemical and Materials Science Research

MRI：为化学和材料科学研究购买 400 MHz 核磁共振控制台升级版

• 批准号: 1726173
• 负责人: Aaron Sadow
• 金额: $ 28.65万
• 依托单位: Iowa State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2020-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1726173&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; Nuclear

This award is supported by the Major Research Instrumentation (MRI) and the Chemistry Research Instrumentation (CRIF) pPograms. Professor Aaron Sadow from Iowa State University and colleagues Yan Zhao, Levi Stanley, Martin Thuo and Sarah Cady have acquired an upgrade for a 400 MHz nuclear magnetic resonance (NMR) spectrometer by equipping it with a new console and a liquid-nitrogen, cooled cryoprobe as well as a flow NMR system to monitor kinetics. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as the study of biologically relevant species. In general, NMR spectroscopy is one of the most powerful tools available to chemists to study the structure of molecules. It is used to identify unknown substances, to understand the specific arrangements of atoms within molecules, and to study the changes of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is important to chemists who are carrying out frontier research. The results from these NMR studies have an impact in synthetic organic/inorganic chemistry, materials chemistry, forensics and biochemistry. This instrument is an integral part of teaching as well as research performed by undergraduate students via independent student research and traditional academic coursework as well as researchers and graduate students and high school students who participate in outreach activities. The NMR center also offers data collection and analysis for nearby industries.This NMR spectrometer enhances research and education at all levels. It especially benefits the development of synthetic materials to produce bacterial biofilms and studies of catalytic reaction pathways. The spectrometer is also used in developing catalysts for new reactions that couple carbon-hydrogen and carbon-halogen bond activation with carbon-carbon and carbon-heteroatom bond formation and for engineering soft materials, one bond at a time.

该奖项得到主要研究仪器 (MRI) 和化学研究仪器 (CRIF) pPograms 的支持。爱荷华州立大学的 Aaron Sadow 教授及其同事赵岩、Levi Stanley、Martin Thuo 和 Sarah Cady 对 400 MHz 核磁共振 (NMR) 波谱仪进行了升级，为其配备了新的控制台和液氮冷却冷冻探头以及用于监测动力学的流式核磁共振系统。该光谱仪可用于多种领域的研究，例如加速具有重大经济意义的化学反应的领域，以及生物学相关物种的研究。一般来说，核磁共振波谱是化学家研究分子结构最强大的工具之一。它用于识别未知物质，了解分子内原子的具体排列，以及研究溶液或固态中分子之间相互作用的变化。对于进行前沿研究的化学家来说，使用最先进的核磁共振波谱仪非常重要。这些核磁共振研究的结果对合成有机/无机化学、材料化学、法医学和生物化学产生影响。该工具是本科生通过独立学生研究和传统学术课程作业以及参与外展活动的研究人员、研究生和高中生进行的教学和研究的一个组成部分。 NMR 中心还为附近的行业提供数据收集和分析。这款 NMR 波谱仪增强了各个级别的研究和教育。它特别有利于生产细菌生物膜的合成材料的开发和催化反应途径的研究。该光谱仪还用于开发新反应的催化剂，将碳-氢和碳-卤素键的活化与碳-碳和碳-杂原子键的形成结合起来，以及用于工程软材料，一次一个键。