Genealogical Studies of Polyploidy Using Tetraploid Zea Perennis (Poacease) as a Model System

以四倍体玉米（Poacease）为模型系统进行多倍体谱系研究

• 批准号: 9815855
• 负责人: Brandon Gaut
• 金额: $ 10万
• 依托单位: University of California-Irvine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-04-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9815855&HistoricalAwards=false
• 关键词: Genealogical; Studies; Polyploidy; Using; Tetraploid

9815855GautPolyploidy is a mechanism that multiplies the chromosomal content of an organism, a process that is particularly important in plants. Approximately 70% of all plants have a polyploid origin, and major crops like wheat and cotton owe their agricultural productivity to recent polyploid events. Little is known, however, about the evolutionary fate of polyploid genes, and this is a broad gap in our understanding of plant genetics. This study focuses on genetic variation in Zea perennis, a polyploid that is a close relative of maize (corn). The goals of the study are to: i) measure genetic variation in polyploid genes, ii) analyze the pattern of genetic variation to determine the population forces acting on duplicated genes, and iii) determine whether the polyploid process occurred once or multiple times. Genetic variation will be measured by sequencing DNA of 3 genes from 30 individuals representing Zea perennis and its presumed ancestor, Z. diploperennis. The data from this project will be analyzed with data from previous studies of maize and other wild relatives.As the first study of its kind, the proposed work has the potential to provide unique and general insights into a broad array of issues, such as the way polyploids form, the mode of inheritance of polyploid genes, and the relative importance of evolutionary processes like recombination, mutation and natural selection in shaping genetic diversity in a polyploid. H:\popbio\abstracts\fy1999\9815855 (Gaut abstract)

9815855Gaut 多倍体是一种使生物体染色体含量倍增的机制，这一过程在植物中尤为重要。大约 70% 的植物具有多倍体起源，小麦和棉花等主要作物的农业生产力归功于最近的多倍体事件。然而，人们对多倍体基因的进化命运知之甚少，这是我们对植物遗传学理解的巨大差距。这项研究的重点是玉米（Zea perennis）的遗传变异，玉米是一种多倍体，是玉米的近亲。该研究的目标是：i）测量多倍体基因的遗传变异，ii）分析遗传变异的模式以确定作用于重复基因的群体力量，以及iii）确定多倍体过程是发生一次还是多次。遗传变异将通过对 30 个代表多年生玉米及其假定祖先 Z. diloperennis 的 30 个个体的 3 个基因进行 DNA 测序来测量。该项目的数据将与以前对玉米和其他野生近缘种的研究数据进行分析。作为此类研究中的第一项，拟议的工作有可能为一系列广泛的问题提供独特和普遍的见解，例如多倍体的形成方式、多倍体基因的遗传模式，以及重组、突变和自然选择等进化过程在形成多倍体遗传多样性方面的相对重要性。 H:\popbio\abstracts\fy1999\9815855（高特摘要）