High Throughput Instrumentation in Introductory Analytical Chemistry

分析化学入门中的高通量仪器

• 批准号: 9651270
• 负责人: Paul Endres
• 金额: $ 1.15万
• 依托单位: Bowling Green State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-06-01 至 1998-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9651270&HistoricalAwards=false
• 关键词: Throughput; Instrumentation; Introductory; Analytical; Chemistry

Instrumentation is essential to modern laboratory work, but is frequently too expensive for introductory courses in which many students require simultaneous access. This situation often results in very limited access to instruments and, often, to the use of low-cost, low-performance instruments. If appropriate instruments were selected and utilized, with careful thought to high throughput and off-line data handling, many of the time and funding bottlenecks would be greatly reduced. This project is utilizing three such instruments to upgrade the introductory courses in quantitative chemical analysis dramatically at the freshman and sophomore levels. Atomic Absorption/Atomic Emission spectroscopy is a proven technique that is being used to process many individual student samples rapidly. Newly developed miniature spectrometers can be used as low-cost, rapid instruments for a variety of spectroscopic and spectrophotometric measurements. The basic technology is proven, but considerable development work is required to convert this into a routine teaching instrument. Gas chromatographs are being modified with multibore capillary columns to provide high resolution in less than 5 minutes per sample, with no need for time-consuming temperature programming. One of the goals of this project is to develop, critically evaluate, and distribute instructional applications for these newer technologies. The department also expects to provide much more realistic and modern analytical experiences for introductory chemistry students. This objective requires the use of updated technology, but can be facilitated by a major restructuring of the way that student laboratories are organized and operated. The project is directly affecting approximately 100 students per year, especially those majoring in chemistry, biology, geology, medical technology, and environmental sciences.

仪器对于现代实验室工作至关重要，但对于许多学生需要同时访问的入门课程来说仪器往往过于昂贵。这种情况常常导致仪器的使用非常有限，并且常常导致使用低成本、低性能的仪器。如果选择和使用适当的仪器，并仔细考虑高通量和离线数据处理，许多时间和资金瓶颈将大大减少。 该项目正在利用三个这样的仪器来大幅升级大一和大二学生的定量化学分析入门课程。原子吸收/原子发射光谱是一种经过验证的技术，可用于快速处理许多单独的学生样本。新开发的微型光谱仪可用作各种光谱和分光光度测量的低成本、快速仪器。基本技术已得到证实，但需要大量的开发工作才能将其转化为常规教学仪器。气相色谱仪正在采用多孔毛细管柱进行改造，以便在不到 5 分钟的时间内获得每个样品的高分辨率，无需耗时的温度编程。 该项目的目标之一是开发、严格评估和分发这些新技术的教学应用程序。该系还希望为化学入门学生提供更加现实和现代的分析体验。这一目标需要使用更新的技术，但可以通过对学生实验室的组织和运营方式进行重大重组来促进。该项目每年直接影响约 100 名学生，特别是化学、生物学、地质学、医疗技术和环境科学专业的学生。