Advanced Graphene-based Products with Special Luminescent Properties for DNA Sensor

用于 DNA 传感器的具有特殊发光特性的先进石墨烯产品

• 批准号: 560734-2020
• 负责人: Zhang, Jin
• 金额: $ 2.19万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=705513
• 关键词: Advanced; Graphene; based; Products; Special

The goal of this project is to upgrade the manufacturing process of Saint Jean Carbon, inc (SJC) to develop advanced graphene-based products, including graphene quantum dots with special luminescence properties and reduced graphene oxide nanosheets modified with chemical functional groups. In addition, a protocol of the graphene-based DNA sensor will be designed and developed to quickly detect single-strand DNA sequences. Three major research activities are (1) Development of physical and chemical processes carbon-based nanostructured with special luminescent properties; (2) systematical characterization of the microstructures and photoluminescent properties of engineered carbon-based nanostructures before and after bioconjugation; (3) development of a proof of concept on homogenous DNA sensor for quick detecting low concentration of DNA sequence. SJC will use the results of the collaborative project to upgrade the pilot plant in Oakville, Ontario to scale-up the advanced graphene-based products. In addition, trainees involved in this project will be able to gain solid experience in the development of graphene-based systems with special properties.

该项目的目的是升级Saint Jean Carbon，Inc（SJC）的制造过程，以开发基于先进的石墨烯的产品，包括具有特殊发光特性的石墨烯量子点和用化学官能团修饰的氧化石墨烯纳米片减少。此外，将设计和开发基于石墨烯的DNA传感器的方案，以快速检测单链DNA序列。三个主要的研究活动是（1）具有特殊发光特性的碳基纳米结构的物理和化学过程的开发； （2）生物结合前后工程碳基纳米结构的微结构和光致发光特性的系统表征； （3）开发在同质DNA传感器上的概念证明，以快速检测低浓度的DNA序列。 SJC将使用协作项目的结果来升级安大略省奥克维尔的飞行员工厂，以扩大基于石墨烯的先进产品。此外，参与该项目的学员将能够在开发具有特殊属性的石墨烯系统的开发方面获得良好的经验。