Base Metal Complex-Catalyzed Fluoroalkene Transformations: New Routes to Commercially Valuable Fluorocarbon Compounds

贱金属络合物催化氟烯烃转化：生产具有商业价值的氟碳化合物的新途径

• 批准号: 537773-2018
• 负责人: Baker, Ralph
• 金额: $ 2.38万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=684500
• 关键词: Base; Metal; Complex; Catalyzed; Fluoroalkene

Canada is a significant user of refrigerants for a number of applications within its built environment, including refrigeration for food, recreation (skating and curling rinks), and residential and commercial buildings. Fluoroalkenes have recently been identified as the newest generation of refrigerants, propellants and blowing agents due to their greatly reduced global warming potential vs. currently used hydrofluorocarbons. Typical routes to fluoroalkenes, however, are currently energy intensive and often employ toxic reagents such as heavy metals and hydrogen fluoride. In this project we will build on exciting new base-metal catalyzed routes to fluoroalkenes using a newly constructed integrated gas manifold for producing, purifying and isolating gases on the multigram scale. Using readily tunable nickel and copper complex catalysts, commercially available fluoroalkenes will be converted into a host of new fluorocarbon compounds that can serve as more economically and environmentally friendly alternatives to those currently in use. Our ability to prepare a variety of new fluoroalkenes not readily accessible by current routes will allow our industry partner, Arkema(in Canada since 1957) to test them as refrigerants, propellants and blowing agents, as well as new monomers for high-value fluoropolymers. In addition to advancing our fundamental knowledge of base metal organofluorine chemistry, identification of economical routes to new industrially important fluorocarbon products will also contribute to a reduction in global warming currently attributed to fluorocarbon emissions. Moreover, our co-workers will be trained in an exciting area of organofluorine chemistry that offers new applications in pharma and agrichemicals as well as advanced materials.

加拿大是其建筑环境中许多应用制冷剂的重要用户，包括食品、娱乐（溜冰场和冰壶场）以及住宅和商业建筑的制冷。氟烯烃最近被认为是最新一代的制冷剂、推进剂和发泡剂，因为与目前使用的氢氟碳化合物相比，它们大大降低了全球变暖的潜力。然而，目前制备氟代烯烃的典型途径是能源密集型的，并且经常使用有毒试剂，例如重金属和氟化氢。在这个项目中，我们将建立令人兴奋的新型贱金属催化氟代烯烃路线，使用新构建的集成气体歧管来生产、纯化和分离数克规模的气体。使用易于调节的镍和铜络合物催化剂，市售的氟代烯烃将被转化为许多新型碳氟化合物，这些化合物可以作为目前使用的碳氟化合物的更经济、更环保的替代品。我们有能力制备目前途径不易获得的各种新型氟代烯烃，这将使我们的行业合作伙伴阿科玛（自 1957 年起在加拿大）能够将它们作为制冷剂、推进剂和发泡剂以及高价值含氟聚合物的新单体进行测试。除了提高我们对贱金属有机氟化学的基础知识外，确定生产具有重要工业意义的新型碳氟化合物产品的经济途径也将有助于减少目前由于碳氟化合物排放而导致的全球变暖。此外，我们的同事将接受令人兴奋的有机氟化学领域的培训，该领域为制药和农用化学品以及先进材料提供新的应用。