Development and validation of synthetic bone and soft tissue analogues for surgical training (Phase I)

用于外科训练的合成骨和软组织类似物的开发和验证（第一阶段）

• 批准号: 476890-2015
• 负责人: Anglin, Carolyn
• 金额: $ 9.11万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Idea to Innovation
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=578767
• 关键词: Development; validation; synthetic; bone; soft

Our team has developed a synthetic bone analogue that mimics the tactile feel of bone when using orthopaedic instruments. Residents can use this training system to learn and practice key orthopaedic skills. To date, surgical training has usually occurred on patients in a master-apprentice model. However, physical and virtual simulators are increasingly seen as essential to a resident's education, to improve patient safety and for more efficient learning. To be effective, they must realistically represent the key features and must be validated. In addition to feeling more like bone than existing models, our models represent a harder outer cortical layer, softer, inner cancellous bone, and a transition between the two. The material properties can be tuned such that they represent weak (osteoporotic), normal or strong bone, and can be shaped in normal or abnormal geometry, and can be seen realistically in an X-ray. Three applications include: pedicle screw placement training for spinal surgery, knee replacement surgery training, and biomechanical testing of implants and instruments. Collaborating with our technology transfer office, Innovate Calgary, our team consists of engineers, a spinal surgeon/entrepreneur, business professor/entrepreneur, biochemist, veterinary anaesthesiologist/educator and artist. End users interested in using the bone models include orthopaedic companies, academic training centres and researchers. The purpose of the proposed research is to: improve the models based on user feedback; create new bone models; reduce manufacturing costs further (they are already inexpensive, but could be even more so with automation); add realistic soft tissues; create validated teaching modules; validate the models mechanically and with orthopaedic residents; and test business assumptions. Our goal is to use the results of this research to create a spin-off company, benefiting Canada and improving patient safety.

我们的团队开发了一种合成的骨头类似物，该骨骼模拟使用骨科仪器时骨骼的触觉。居民可以使用此培训系统来学习和练习关键的骨科技能。迄今为止，通常在大师批准模型的患者上进行了手术训练。但是，物理和虚拟模拟器越来越被视为对居民的教育至关重要，以提高患者的安全和更有效的学习。为了有效，它们必须实际代表关键特征，并且必须得到验证。 除了感觉比现有模型更像骨头外，我们的模型还代表了更坚硬的外层皮层，柔软，内部取消骨骼以及两者之间的过渡。可以调节材料特性，以使它们代表弱（骨质疏松），正常或强骨，并且可以在正常或异常的几何形状中形成，并且可以在X射线中实际看到。三个应用包括：用于脊柱手术的椎弓根螺钉放置训练，膝盖置换手术训练以及植入物和仪器的生物力学测试。 与我们的技术转移办公室创新卡尔加里合作，我们的团队由工程师，脊柱外科医生/企业家，商业教授/企业家，生物化学家，兽医麻醉师/教育家和艺术家组成。有兴趣使用骨骼模型的最终用户包括骨科公司，学术培训中心和研究人员。 拟议研究的目的是：根据用户反馈改进模型；创建新的骨模型；进一步降低制造成本（它们已经很便宜，但自动化可能会更多）；添加逼真的软组织；创建经过验证的教学模块；与骨科居民机械验证模型；和测试业务假设。我们的目标是利用这项研究的结果来创建一家衍生公司，使加拿大受益并提高患者安全。