Rigid organic dications for the control of hair morphology

用于控制头发形态的刚性有机阳离子

• 批准号: 465470-2014
• 负责人: Berg, David
• 金额: $ 0.38万
• 依托单位: University of Victoria
• 依托单位国家: 加拿大
• 项目类别: Engage Plus Grants Program
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=560185
• 关键词: Rigid; organic; dications; control; hair

The purpose of this project is to develop molecules that will adhere to hair providing crosslinks between strands that allow for style retention during curling or straightening. The strategy used here is to develop rigid organic molecules with a well defined and tunable geometry that contain positively charged head groups. Initially these head groups will be ammonium cations that have a strong affinity for the negatively charged surface of hair. Incorporation of additional cations or hydrogen bonding units is possible to increase the binding affinity of the molecules. The core of these molecules, while not engaged in binding the hair strands, can be varied to contain a wide range of secondary functionality including for example, fluorescent, temperature or pH sensitive dyes. We intend to provide gram quantities of these molecules to SLI Beauty for testing on hair tresses in order to identify which combinations of functionality and core groups offer the most commercial promise.

该项目的目的是开发能够粘附在头发上的分子，在发丝之间提供交联，从而在卷曲或拉直过程中保持发型。这里使用的策略是开发具有明确且可调的几何形状的刚性有机分子，其中包含带正电的头部基团。最初，这些头部基团是铵阳离子，对头发的带负电荷的表面具有很强的亲和力。掺入额外的阳离子或氢键单元可以增加分子的结合亲和力。这些分子的核心虽然不参与结合发丝，但可以变化以包含多种辅助功能，包括例如荧光、温度或 pH 敏感染料。我们打算向 SLI Beauty 提供克数量的这些分子，用于对发束进行测试，以确定哪些功能和核心基团的组合最具商业前景。