Signal and image processing methods for studying human ventricular fibrillation

研究人体心室颤动的信号和图像处理方法

• 批准号: 386738-2010
• 负责人: Umapathy, Karthikeyan
• 金额: $ 2.04万
• 依托单位: Ryerson University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=529042
• 关键词: Signal; image; processing; methods; studying

The heart is a versatile electro-mechanical organ that is driven by autonomously generated rhythmic electrical pulses within it. When the electrical generation or conduction system of the heart malfunctions or is diseased, the heart quivers with arrhythmic and chaotic contractions, resulting in ineffective or cessation of blood circulation to vital organs. This medical condition in general is termed as cardiac arrhythmia. When this happens in the ventricles (lower chambers of the heart responsible for pushing out blood), a serious medical condition called ventricular fibrillation (VF) occurs. VF, if untreated within minutes of its occurrence, leads to sudden cardiac death (SCD). Every year in North America about 350,000 SCDs (with 45,000 of them in Canada, i.e. an SCD every 12 minutes) are reported, most of which are VF related. In spite of its importance, and active research over 100 years, the mechanism behind human VF is still elusive because of the non-stationary nature of the process and ethical/practical limitations in studying human VF.

心脏是一种多功能的电力器官，由它内部自主产生的节奏脉冲驱动。当心脏故障或患病的发电或传导系统时，心脏颤抖的心律失常和混乱收缩，导致血液循环无效或停止至重要器官。总体而言，这种疾病被称为心律不齐。当这种情况发生在心室中（心脏的下部腔室负责排出血液）时，会发生一种严重的医疗状况，称为心室纤颤（VF）。 VF如果在发生后几分钟内未经治疗，则会导致心脏突然死亡（SCD）。每年在北美每年都有大约35万SCD（其中有45,000个在加拿大，即每12分钟的SCD），其中大多数与VF有关。尽管它的重要性和100年以来的积极研究，但人类VF背后的机制仍然难以捉摸，因为该过程的非平稳性质以及研究人VF的道德/实践局限性。