Biomolecular assemblies and soft nanostructured materials

生物分子组装体和软纳米结构材料

• 批准号: 327200-2007
• 负责人: Harden, James
• 金额: $ 3.79万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=481621
• 关键词: Biomolecular; assemblies; soft; nanostructured; materials

The proposed research program combines studies in two thematic areas of soft matter: soft glassy nanostructured materials and protein-based biomolecular assemblies. These studies will combine light scattering, diffusing wave spectroscopy, mechanical rheometry, and x-ray photon correlation spectroscopy methods with materials synthesis and computational modeling. In the research program on soft glassy materials, we will study the formation and aging of several model soft nanostructured materials (temperature reversible nanoparticle gels, nanoemulsions under shear, and polymer melts and elastomers near the glass transition) with a focus on understanding the effects of mechanical deformation on the formation and aging processes. In the research program on protein-based biomolecular assemblies, we will develop new elastomeric protein materials (associating protein networks and elastomeric protein polymers), and investigate the roles of their modular domains in determining their structural and viscoelastic properties.

拟议的研究计划结合了在软物质的两个主题领域中的研究：软玻璃纳米结构材料和基于蛋白质的生物分子组件。这些研究将与材料合成和计算建模相结合光散射，扩散波光谱，机械流变学和X射线光子相关方法。 在软玻璃材料的研究计划中，我们将研究几种模型软纳米结构材料的形成和老化（温度可逆的纳米颗粒凝胶，剪切下的纳米乳液，以及玻璃过渡附近的聚合物融化和弹性体），重点是理解理解的影响形成和老化过程的机械变形。 在基于蛋白质的生物分子组件的研究计划中，我们将开发新的弹性蛋白质材料（关联蛋白质网络和弹性蛋白聚合物），并研究其模块化结构域在确定其结构和粘弹性特性中的作用。