Micropeptides as a tool for intracellular signalling and regulation in higher eukaryotes

微肽作为高等真核生物细胞内信号传导和调节的工具

• 批准号: 238940-2006
• 负责人: Pellegrini, Luca
• 金额: $ 2.06万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=337096
• 关键词: Micropeptides; tool; intracellular; signalling; regulation

A large number of micropeptides have been found in the cytoplasm and their potential structural ability to regulate intracellular signal transduction exists. However, their participation in this process is still largely unexplored. This study will investigate the function of micropeptides of mitochondrial origin, thereby addressing the question of whether micropeptides, either produced by the cell as part of protein catabolism or not, have signalling and/or regulatory ability inside the cell.

在细胞质中发现了大量的微肽，它们具有调节细胞内信号转导的潜在结构能力。然而，他们对这一过程的参与在很大程度上仍未被探索。这项研究将研究线粒体来源的微肽的功能，从而解决细胞产生的微肽（作为蛋白质分解代谢的一部分或不）是否在细胞内具有信号传导和/或调节能力的问题。