Keystone Symposia Annual Meeting Series on Diabetes

Keystone 糖尿病研讨会年会系列

• 批准号: 8994735
• 负责人: DAVID L. WOODLAND
• 金额: $ 1.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-01-13 至 2019-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8994735
• 关键词: Accounting; Address; Aging; Amputation; Area; Biological Models; Blindness; Cardiac; Circadian Rhythms; Clinical Investigator; Collaborations; Congenital Abnormality; Data; Defect; Diabetes Mellitus; Disease; Fatty Acids; Fostering; Functional disorder; Health; Heart Diseases; Heart failure; Human; Human Pathology; Hypertension; Insulin Resistance; Kidney Diseases; Knowledge; Mentors; Metabolic; Metabolic Diseases; Metabolism; Methodology; Mitochondria; Molecular; Nerve Degeneration; New Mexico; Obesity; Outcome; Periodontal Diseases; Process; Public Health; Research; Research Personnel; Role; Scientist; Series; Signal Transduction; Skeletal Muscle; Stroke; System; Tissues; Wound Healing; base; career development; clinical practice; design; energy balance; glucose production; meetings; novel; posters; programs; symposium

DESCRIPTION (provided by applicant): Support is requested for a series of annual Keystone Symposia meetings on the topic of Diabetes. The first meeting in the series will be held in 2015 and is entitled Diabetes and Metabolic Dysfunction, and is being organized by Jeffrey E. Pessin, Alan R. Saltiel and Deborah M. Muoio. The meeting will be held in Santa Fe, New Mexico from January 27 - February 1, 2015. The 2015 meeting will address several cutting edge aspects of molecular, cellular, tissue and integrative system metabolism that account for the metabolic defects that occur in diabetes and obesity. Several of these themes overlap with the concurrent meeting on Mitochondria, Metabolism and Heart Failure and four concurrent sessions are planned. These concurrent sessions will address distinct and novel aspects of normal and dysregulation muscle (skeletal and cardiac) intracellular signaling, mitochondria function/dynamics, aging and energy balance. The meeting organizers have selected leaders in each of these respective areas that will not only address basic and integrative mechanisms in model systems, but several will address these issues in human pathology. The diabetes-specific sessions (4) reflect several key aspects of metabolic dysregulation in which novel information is currently forthcoming causing a paradigm shift in over our previous understanding of these processes. These include new information about tissue cross-talk, the inter-relationship between the control of glucose production and fatty acid synthesis that underlies selective insulin resistance and the role of normal and dysregulated circadian rhythms on metabolic processes. These new cutting-edge advances will provide novel and exciting new findings for the basis of new future research directions.

描述（由申请人提供）：请求支持一系列有关糖尿病主题的年度 Keystone 研讨会。该系列的第一次会议将于 2015 年举行，题为“糖尿病和代谢功能障碍”，由 Jeffrey E. Pessin、Alan R. Saltiel 和 Deborah M. Muoio 组织。会议将于 2015 年 1 月 27 日至 2 月 1 日在新墨西哥州圣达菲举行。2015 年会议将讨论分子、细胞、组织和综合系统代谢的几个前沿问题，这些问题解释了糖尿病和糖尿病中发生的代谢缺陷。肥胖。其中几个主题与同期举行的线粒体、新陈代谢和心力衰竭会议重叠，并计划举行四场同期会议。这些同期会议将讨论正常和失调肌肉（骨骼和心脏）细胞内信号传导、线粒体功能/动力学、衰老和能量平衡的独特和新颖的方面。会议组织者选出了各个领域的领导者，他们不仅将解决模型系统中的基本和综合机制，而且还将解决人类病理学中的这些问题。糖尿病专题会议 (4) 反映了代谢失调的几个关键方面，其中当前即将出现的新信息导致我们以前对这些过程的理解发生范式转变。其中包括有关组织串扰的新信息、选择性胰岛素抵抗的葡萄糖产生控制和脂肪酸合成之间的相互关系，以及正常和失调的昼夜节律对代谢过程的作用。这些新的前沿进展将为未来新的研究方向的基础提供新颖且令人兴奋的新发现。