Promoting Cancer-related Behavior Change through Positive Emotions (PQ4)

通过积极情绪促进癌症相关行为改变（PQ4）

基本信息

批准号：
8847231
负责人：
BARBARA LEE FREDRICKSON
金额：
$ 51.58万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-08 至 2018-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8847231
关键词：
Adherence Adopted Affect Alcohol consumption Alcohols American Cancer Society Attention Awareness Behavior Behavioral Biological Brain Cardiac Carrots - dietary Chronic Disease Conscious Data Diet Eating Ego Emotional Endocrine Goals Health Health Benefit Health Promotion Health behavior Incidence Individual Individual Differences Inflammation Intervention Knowledge Learning Life Life Style Link Long-Term Effects Love Maintenance Malignant Neoplasms Measures Meditation Mental Depression Modeling Nutritional Outcome Oxytocin Pain Patient Self-Report Personal Satisfaction Physical activity Physiological Placebo Control Positioning Attribute Preventive Process Public Health Randomized Research Resolution Resources Rest Risk Risk Behaviors Role Science Seeds Self-control as a personality trait Stream Stress System Testing Theoretical model Time Tobacco Tobacco use Translating Translational Research Work arm base behavior change biopsychosocial blind cancer risk clinical practice evidence base experience flexibility follow-up healthy lifestyle improved indexing innovation mindfulness mindfulness meditation novel positive emotional state prevent programs psychologic public health intervention research study resilience response skills theories trait unhealthy lifestyle

项目摘要

DESCRIPTION (provided by applicant): The American Cancer Society estimates that 62% of all cancers could be prevented altogether through lifestyle change. Despite good intentions, people's attempts to alter their behaviors known to increase cancer risk - related to diet, physica activity, tobacco and alcohol use - often fail, which ultimately increases their risks for various cancers. In response to NCI's Provocative Question 4, the overarching goal of the proposed research is to investigate the role of positive emotions in facilitating successful lifestyle chang, defined as long-term adherence to cancer- preventive behaviors (e.g., nutritious eating, physical activity, tobacco, and alcohol use). An innovative upward spiral model of lifestyle change integrates multiple streams of research in basic behavioral and brain sciences to position positive emotions as key active ingredients that not only seed non-conscious motivational pulls toward newly-adopted cancer-preventive behaviors, but also reshape key biopsychosocial resources in ways that increase the subsequent positive emotion yield of multiple cancer-preventive behaviors, creating a self- sustaining dynamic system. A longitudinal, dual-blind, placebo-controlled field experiment tests this new model by targeting three Specific Aims. These aims are: (1) to identify biopsychosocial resources that moderate the link between cancer-preventive behaviors and their positive emotion yield; (2) to test whether and how positive emotions, experienced in daily life, produce a psychological propensity for wellness through the combined presence of (a) increases in non-conscious motives for cancer-preventive behaviors and (b) increases in biopsychosocial resources; and (3) to test whether positive emotions and a psychological propensity for wellness predict increasing and sustained cancer-preventive behaviors and improved health-related outcomes at 18-month follow-up. The proposed study tests the novel upward spiral model in daily life with densely repeated measures and physiological, behavioral, endocrine, and self- report indices of health-related outcomes. This program of translational research stands to reshape public health interventions and unlock hidden opportunities to drastically reduce the incidence of cancer.

描述（由申请人提供）：美国癌症协会估计，62% 的癌症可以通过改变生活方式来完全预防。尽管意图良好，但人们尝试改变已知会增加癌症风险的行为（与饮食、体育活动、吸烟和饮酒有关）往往会失败，这最终会增加他们患各种癌症的风险。针对 NCI 的挑衅性问题 4，拟议研究的总体目标是调查积极情绪在促进成功生活方式改变中的作用，生活方式改变的定义是长期坚持癌症预防行为（例如营养饮食、体力活动、吸烟）。和饮酒）。生活方式改变的创新螺旋上升模型整合了基础行为和脑科学的多个研究流，将积极情绪定位为关键活性成分，不仅为新采取的癌症预防行为注入无意识动机，而且重塑了关键的生物心理社会以增加多种癌症预防行为随后的积极情绪产量的方式整合资源，创建一个自我维持的动态系统。纵向、双盲、安慰剂对照现场实验通过针对三个特定目标来测试这个新模型。这些目标是：（1）确定生物心理社会资源，以调节癌症预防行为与其积极情绪产生之间的联系；（2）测试日常生活中经历的积极情绪是否以及如何通过（a）癌症预防行为的无意识动机的增加和（b）生物心理社会资源的增加的综合存在产生健康的心理倾向； (3) 测试积极情绪和健康心理倾向是否可以预测 18 个月随访时癌症预防行为的增加和持续以及健康相关结果的改善。拟议的研究通过密集重复的测量以及健康相关结果的生理、行为、内分泌和自我报告指数来测试日常生活中的新型螺旋上升模型。这项转化研究计划将重塑公共卫生干预措施，并释放隐藏的机会，从而大幅降低癌症的发病率。