Role of Chromogranin A in Metabolic Syndrome

嗜铬粒蛋白 A 在代谢综合征中的作用

• 批准号: 8195907
• 负责人: SUSHIL K MAHATA
• 金额: --
• 依托单位: VA SAN DIEGO HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195907
• 关键词: Adenosine Monophosphate; Adipocytes; Adrenal Cortex Hormones; Adrenergic Receptor; Affect; Attenuated; Baroreflex; Blood Glucose; Blood Pressure; C-Peptide; CHGA gene; Cardiovascular Diseases; Catecholamines; Cells; Chromogranin A; Chromogranins; Chronic; Corticosterone; Coupled; Development; Diabetes Mellitus; Diabetic mouse; Diet; Drosophila pros protein; Engineering; Equilibrium; Essential Hypertension; Euglycemic Clamping; Fatty acid glycerol esters; Gluconeogenesis; Gluconeogenesis Inhibition; Glucose; Glucose Clamp; Glucose Intolerance; Glycogen; Goals; Heart Rate; Hepatic; Hepatocyte; Hormones; Hyperglycemia; Hypertension; Hypoglycemia; Hypotension; Insulin; Insulin Resistance; Knockout Mice; Lipids; Lipodystrophy; Liver; Malaise; Mediating; Metabolic; Metabolic Diseases; Metabolic syndrome; Metabolism; Modeling; Morbidity - disease rate; Mus; Muscle; Neurosecretory Systems; Nicotine; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Pancreas; Pathway interactions; Patients; Peptides; Phenotype; Plasma; Play; Protein Family; Protein Kinase; Proteolytic Processing; Pyruvate; Regulation; Role; Structure of beta Cell of islet; Supplementation; Testing; Therapeutic Effect; Time; Tissues; United States; Variant; Vasodilator Agents; Wild Type Mouse; alpha-adrenergic receptor; base; beta-adrenergic receptor; blood glucose regulation; cardiovascular risk factor; chromogranin A (344-364); db/db mouse; desensitization; diabetic; feeding; glucose disposal; glucose production; glucose tolerance; glucose transport; glucose uptake; glycogenolysis; heart rate variability; human NOS3 protein; improved; indexing; insight; insulin secretion; insulin sensitivity; insulin tolerance; member; mortality; mouse model; novel; pancreastatin; peptide hormone; prevent; receptor function; secretogranins; vasostatin