Administrative Core

行政核心

• 批准号: 8033892
• 负责人: JAMES R HEBERT
• 金额: $ 10.65万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8033892
• 关键词: Address; African American; Behavioral; Cancer Control; Cancer Etiology; Climate; Communities; Community Networks; Dedications; Development; Diagnosis; Disease; Education; Elements; Environment; Feedback; Funding; Goals; Incidence; Intervention; Knowledge; Life; Literature; Longevity; Malignant Neoplasms; Methods; Mission; Population; Procedures; Public Health; Quality of life; Research; Scientist; Services; South Carolina; Testing; Time; Training; Translational Research; Work; base; cancer health disparity; community based participatory research; health disparity; high risk; improved; innovation; knowledge base; mortality; next generation; prevent; programs; success; successful intervention

South Carolina Cancer Disparities Community Network-ll builds upon the many successes we achieved as a Community Networks Program funded in CNP-I. SCCDCN-ll's overarching goal is to contribute materially to: understanding the underiying causes of cancer-related health disparities; discovering and developing effective innovations to lower incidence, improve survival, and reduce suffering; delivering these innovations to high-risk populations; and, finally, moving them to widespread dissemination. We focus on African Americans (AAs) in South Carolina, a group in a region with much higher-than-average cancer incidence and extraordinarily high mortality given incidence. Our goal will be realized by achieving these Specific Aims: 1. To use the full range of expertise represented in our academic and community partnerships, to increase the knowledge base needed to understand which biomedical and behavioral procedures are most likely to prevent and control cancer in the high-risk African-American communities in South Carolina; 2. Based on discoveries derived from thorough understanding ofthe literature, careful consideration of our own descriptive studies and observations, and feedback from community partners, to develop and test interventions that are likely to reduce cancer incidence, downstage disease at time of diagnosis, increase longevity, and improve gualitv of life in people with cancer; 3. To deliver interventions shown to be effective to places of greatest receptivity and public health need and to evaluate them in terms of generalizability (i.e., external validity); and 4. To disseminate results from successful interventions in the form of intervention "packages" within our communities in South Carolina and to work with national partners to determine and distinguish universal elements that will work most (or at least many) places and others that are more place- and culture-specific. The success of SCCDCN-ll is predicated on: strong community support; dedication to the principles of community-based participatory research; understanding that the philosophical underpinnings and practical methods of applying knowledge are essentially the same across interdisciplinary, translational and communitybased participatory research; that the tripartite missions of research, education, and service are both inseparable and highly interdependent; and that training ofthe next generation of scientists dedicated to the highest ideals of community-based participatory, interdisciplinary, and translational research is necessary in order to reduce, and then finally eliminate cancer-related health disparities.

南卡罗来纳州癌症差异社区网络-ll 建立在我们作为 CNP-I 资助的社区网络计划所取得的许多成功的基础上。 SCCDCN-ll 的总体目标是为以下方面做出实质性贡献： 了解癌症相关健康差异的根本原因；发现和开发有效的创新，以降低发病率、提高生存率并减少痛苦；向高风险人群提供这些创新；最后，将它们广泛传播。我们重点关注南卡罗来纳州的非裔美国人 (AA)，该群体的癌症发病率远高于平均水平，且发病率死亡率极高。我们的目标将通过实现以下具体目标来实现： 1. 利用我们学术和社区合作伙伴关系中所代表的全方位专业知识，增加所需的知识库，以了解哪些生物医学和行为程序最有可能预防和控制南卡罗来纳州高风险非裔美国人社区的癌症; 2. 基于对文献的透彻理解、仔细考虑我们自己的描述性研究和观察以及社区合作伙伴的反馈而得出的发现，开发和测试可能降低癌症发病率、诊断时疾病阶段、延长寿命的干预措施，并改善癌症患者的生活质量； 3. 向最容易接受和公共卫生需求最大的地方提供经证明有效的干预措施，并根据普遍性（即外部有效性）对其进行评估；和 4. 以干预“一揽子计划”的形式在南卡罗来纳州社区内传播成功干预措施的成果，并与国家合作伙伴合作，确定和区分适用于大多数（或至少许多）地方的普遍要素以及其他更有效的要素。特定地点和文化。 SCCDCN-ll 的成功取决于： 强大的社区支持；致力于以社区为基础的参与性研究的原则；理解跨学科、转化和社区参与性研究的哲学基础和应用知识的实践方法本质上是相同的；研究、教育和服务三方使命是不可分割且高度相互依存的；为了减少并最终消除与癌症相关的健康差距，有必要培训致力于社区参与、跨学科和转化研究最高理想的下一代科学家。