South Carolina Cancer Disparities Community Network -- II

南卡罗来纳州癌症差异社区网络 -- II

• 批准号: 8137138
• 负责人: JAMES R HEBERT
• 金额: $ 78.63万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8137138
• 关键词: South; Carolina; Cancer; Disparities; Community

DESCRIPTION (provided by applicant): South Carolina Cancer Disparities Community Network N's overarching goal is to contribute materially to: understanding the underlying causes of cancer-related health disparities; discovering and developing effective innovations to lower incidence, improving survival, and reducing suffering; delivering these innovations to high-risk populations and moving them to widespread dissemination. We focus on African Americans (AAs) in South Carolina, a group in a region with much higher-than-average cancer incidence and extraordinarily high mortality given incidence. Our goal will be realized by achieving these Specific Aims: 1. to increase the knowledge base needed to understand which biomedical and behavioral procedures are most likely to prevent and control cancer in the high-risk African-American communities in South Carolina; 2. to develop and test interventions that are likely to reduce cancer incidence, downstage disease at time of diagnosis, increase longevity, and improve quality of life in people with cancer; 3. To deliver interventions shown to be effective to places of greatest receptivity and public health need and to evaluate them in terms of generalizability (i.e., external validity); and 4. To disseminate results from successful interventions in the form of intervention "packages" within our communities in South Carolina and to work with national partners to determine and distinguish universal elements that will work most (or at least many) places and others that are more place- and culture-specific. The success of SCCDCN-ll is predicated on: strong community support; dedication to the principles of community-based participatory research; understanding that the philosophical underpinnings and practical methods of applying knowledge are essentially the same across interdisciplinary, translational and community-based participatory research; that the tripartite missions of research, education, and service are both inseparable and highly interdependent; and that training of the next generation of scientists dedicated to the highest ideals of community-based participatory, interdisciplinary, and translational research is necessary in order to reduce, and then finally eliminate cancer-related health disparities.

描述（由申请人提供）：南卡罗来纳州癌症差异社区网络 N 的总体目标是做出实质性贡献： 了解癌症相关健康差异的根本原因；发现和开发有效的创新来降低发病率、提高生存率和减少痛苦；将这些创新成果提供给高危人群并进行广泛传播。我们重点关注南卡罗来纳州的非裔美国人 (AA)，该群体的癌症发病率远高于平均水平，且发病率死亡率极高。我们的目标将通过实现以下具体目标来实现： 1. 增加所需的知识库，以了解哪些生物医学和行为程序最有可能预防和控制南卡罗来纳州高风险非裔美国人社区的癌症； 2. 开发和测试可能降低癌症发病率、在诊断时预防疾病、延长寿命并改善癌症患者生活质量的干预措施； 3. 向最容易接受和公共卫生需求最大的地方提供经证明有效的干预措施，并根据普遍性（即外部有效性）对其进行评估； 4. 以干预“一揽子计划”的形式在南卡罗来纳州社区内传播成功干预措施的成果，并与国家合作伙伴合作，确定和区分适用于大多数（或至少许多）地方和其他地方的普遍要素。更具地点和文化特色。 SCCDCN-ll 的成功取决于： 强大的社区支持；致力于以社区为基础的参与性研究的原则；理解跨学科、转化和基于社区的参与性研究的哲学基础和应用知识的实践方法本质上是相同的；研究、教育和服务三方使命是不可分割且高度相互依存的；为了减少并最终消除与癌症相关的健康差距，有必要培训致力于社区参与、跨学科和转化研究最高理想的下一代科学家。