Pharmaceutical Sciences and Pharmacogenomics

药物科学和药物基因组学

• 批准号: 7892102
• 负责人: FRANCIS C. SZOKA
• 金额: $ 25.99万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7892102
• 关键词: Pharmacogenomics; Pharmacologic Substance; Science

DESCRIPTION (provided by applicant): The Pharmaceutical Sciences and Pharmacogenomics Graduate Program (PSPG) is a cross-disciplinary program that consists of scientists at the University of California, San Francisco (UCSF) working in pharmaceutical sciences, computation and contemporary genetics. This Program encompasses the areas of molecular pharmacology related to drug development including: drug action, drug transport, drug metabolism and drug/gene delivery. The Program also includes the areas of pharmacokinetic/dynamic modeling, pharmacogenomics and bioinformatics applied to genetics/genomics. The Program offers training in these research areas through a core curriculum that encourages a breadth of knowledge about these fields and an elective curriculum that provides in-depth education on specific topics or techniques. Students participate in an ethical conduct in science course. The program immerses young scientists in the culture of science through a seminar program in pharmacogenomics, an annual retreat and seminars from industrial scientists. Students are recruited into the program with undergraduate degrees in the basic sciences and from Doctor of Pharmacy programs. There are 50 students in the program and approximately 10% of the students come from under represented groups. The program capacity was increased in 2000 from 35 students to 60 students and we anticipate reaching the 60 student capacity in 2012. There are 49 training faculty. Our program is one of the very few in the World with faculty expertise that spans the fields of pharmaceutics, genetics and computation; hence the training program is ideally situated to educate future scientific leaders in the emerging research areas at the intersection of these disciplines. The integrative approach has resulted in Ph.D. graduates who have the insights and quantitative scientific tools required for success in the rapidly advancing fields of drug development and pharmacogenomics; consequently graduates from the program are in high demand in academia, government and industry.

描述（由申请人提供）：药物科学和药物基因组学研究生项目 (PSPG) 是一个跨学科项目，由加州大学旧金山分校 (UCSF) 从事药物科学、计算和当代遗传学工作的科学家组成。 该计划涵盖与药物开发相关的分子药理学领域，包括：药物作用、药物转运、药物代谢和药物/基因传递。该计划还包括药代动力学/动力学建模、药物基因组学和应用于遗传学/基因组学的生物信息学领域。 该计划通过核心课程和选修课程提供这些研究领域的培训，核心课程鼓励人们广泛了解这些领域的知识，而选修课程则提供有关特定主题或技术的深入教育。学生参与科学课程中的道德行为。该项目通过药物基因组学研讨会项目、年度静修会和工业科学家研讨会，让年轻科学家沉浸在科学文化中。 该项目招收具有基础科学本科学位和药学博士学位的学生。该项目共有 50 名学生，其中约 10% 的学生来自代表性不足的群体。 2000 年，该项目的容量从 35 名学生增加到 60 名学生，我们预计 2012 年将达到 60 名学生。共有 49 名培训教师。 我们的项目是世界上为数不多的拥有跨越药剂学、遗传学和计算领域的教师专业知识的项目之一；因此，该培训计划非常适合培养这些学科交叉的新兴研究领域的未来科学领袖。综合方法取得了博士学位。拥有在快速发展的药物开发和药物基因组学领域取得成功所需的洞察力和定量科学工具的毕业生；因此，学术界、政府和工业界对该项目的毕业生有很高的需求。