The Institute for Translational Medicine

转化医学研究所

• 批准号: 10632295
• 负责人: Joshua J Jacobs
• 金额: $ 829.87万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-06 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10632295
• 关键词: Accounting; Address; Advocacy; Advocate; Alcohols; Awareness; Behavior Therapy; Behavioral; Biological; Caring; Chicago; Clinical Research; Clinical Sciences; Communication; Communities; Disease; Economics; Education; Employment; Engineering; Ensure; Environment; Ethics; Ethnic Origin; Exposure to; Food; Gender; Goals; Government Agencies; Health; Health Personnel; Health Status; Health system; Healthcare; Hearing; Home; Housing; Human Biology; Illinois; Immigration; Impaired health; Individual; Infrastructure; Injury; Institutes; Institution; Intervention; Investments; Knowledge; Laws; Leadership; Letters; Life Experience; Medical; Medicine; Morbidity - disease rate; Pharmaceutical Preparations; Physical environment; Policies; Poverty; Psychological Factors; Public Health; Race; Regulation; Reporting; Research; Research Personnel; Research Training; Resources; Role; Safety; Schools; Science; Scientist; Seminal; Services; Sex Behavior; Sex Orientation; Smoking; Social Environment; Social Sciences; Social Work; Societies; Special Population; Stream; Structural Racism; System; Tail; Technology; Testing; Training; Translational Research; Transportation; United States National Academy of Sciences; Universities; Violence; Vision; Vulnerable Populations; Work; biological systems; care providers; clinical practice; community engagement; community organizations; design; disorder risk; experience; food insecurity; hazard; health care delivery; health equity; health equity promotion; improved; innovation; land use; lens; meetings; metropolitan; mortality; multidisciplinary; nutrition; portrayal of violence in the media; segregation; social; social determinants; social interventions; tool; translational medicine; underserved minority; Accounting; Address; Advocacy; Advocate; Alcohols; Awareness; Behavior Therapy; Behavioral; Biological; Caring; Chicago; Clinical Research; Clinical Sciences; Communication; Communities; Disease; Economics; Education; Employment; Engineering; Ensure; Environment; Ethics; Ethnic Origin; Exposure to; Food; Gender; Goals; Government Agencies; Health; Health Personnel; Health Status; Health system; Healthcare; Hearing; Home; Housing; Human Biology; Illinois; Immigration; Impaired health; Individual; Infrastructure; Injury; Institutes; Institution; Intervention; Investments; Knowledge; Laws; Leadership; Letters; Life Experience; Medical; Medicine; Morbidity - disease rate; Pharmaceutical Preparations; Physical environment; Policies; Poverty; Psychological Factors; Public Health; Race; Regulation; Reporting; Research; Research Personnel; Research Training; Resources; Role; Safety; Schools; Science; Scientist; Seminal; Services; Sex Behavior; Sex Orientation; Smoking; Social Environment; Social Sciences; Social Work; Societies; Special Population; Stream; Structural Racism; System; Tail; Technology; Testing; Training; Translational Research; Transportation; United States National Academy of Sciences; Universities; Violence; Vision; Vulnerable Populations; Work; biological systems; care providers; clinical practice; community engagement; community organizations; design; disorder risk; experience; food insecurity; hazard; health care delivery; health equity; health equity promotion; improved; innovation; land use; lens; meetings; metropolitan; mortality; multidisciplinary; nutrition; portrayal of violence in the media; segregation; social; social determinants; social interventions; tool; translational medicine; underserved minority

Contact PD/PI: Solway, Julian Chapter O: Overall ABSTRACT ITM 3.0: ADVANCING HEALTH TOWARD HEALTH EQUITY THROUGHOUT METROPOLITAN CHICAGO The University of Chicago – Rush University Institute for Translational Medicine (ITM) was created in 2007 to assemble, integrate, and create the intellectual, administrative, and physical resources required to catalyze research and research training in Clinical and Translational Science. We have trained university scientists and health care providers as well as stakeholders from concerned communities to work together to determine the biological, behavioral, and social determinants of disease; to develop and test interventions directed toward those mechanisms; and to achieve these goals in a way that is rigorous, efficient, ethical, respectful of, and responsive to our communities’ priorities and values. The ITM has capitalized on outstanding intellectual and physical resources throughout UChicago, Rush, and ITM affiliate institutions – Loyola University Chicago, NorthShore University HealthSystem, Advocate Aurora Health Care, and Illinois Institute of Technology – and on substantial multi-institutional investments to build the sustainable infrastructure for a transformative, energetic, and self-improving home for clinical and translational research. Now, we pursue a bold guiding vision for “ITM 3.0” – that reversing the adverse health consequences of structural racism requires accounting for and mitigating the social, environmental, behavioral, and psychological factors (the entire lived experience, which we will call the “sociome”) through which structural racism impairs health. Focus on the sociome is critical because: 1) sociome factors interact with human biology to exacerbate or cause disease and injury, and 2) illness of any origin can compound the negative effects of adverse sociome factors. Since both sociome and biological systems, and their interactions, determine health, our CTSA hub must provide investigators, trainees, and stakeholders with the resources and knowledge to account for and address health disruptors throughout both systems. Our strategy to implement this vision is to create new training mechanisms, research platforms, communications channels, and safeguards against harm to ensure that all ITM investigators and institutions approach health problems with a wider-angle sociome lens in an ethical way. Then, our scientific, institutional, and community stakeholders can together design, test, and disseminate biological and/or sociome-directed interventions at the levels of individual, community, and society to improve mutually defined health concerns. ITM 3.0 will work hand-in-hand with partners throughout Chicagoland and the nation, combining academic rigor with community wisdom to conceptualize, develop and deploy innovative, just, and ethical interventions/practices to achieve our common goal, and so lessen the health impact of structural racism. Project Summary/Abstract Page 244 Contact PD/PI: Solway, Julian

联系PD/PI：Solway，朱利安 o章：总体 抽象的 ITM 3.0：在整个芝加哥大都会的健康平衡方面发展健康 芝加哥大学 - 拉什大学翻译医学研究所（ITM）于2007年创建 组装，整合并创造催化所需的智力，行政和物理资源 临床和转化科学研究和研究培训。我们已经训练过大学科学家， 医疗保健提供者以及有关社区的利益相关者共同努力确定 疾病的生物学，行为和社会决定者；开发和测试干预措施 这些机制；并以严格，高效，道德，尊重和 回应我们社区的优先事项和价值观。 ITM已利用了杰出的知识分子和 整个Uchicago，Rush和ITM会员机构的物理资源 - 芝加哥Loyola University， 北岸大学健康系统，倡导者Aurora Health Care和Illinois技术研究所 - 以及 进行大量的多机构投资，以建立可持续的基础设施 充满活力，自我提高的临床和翻译研究之家。 现在，我们对“ ITM 3.0”进行大胆的指导愿景 - 逆转了不利的健康后果 结构性种族主义需要考虑并减轻社会，环境，行为和 心理因素（整个现场经验，我们称为“社会”） 结构性种族主义会损害健康。专注于社会群体至关重要，因为：1）社会因素与 人类生物学加剧或引起疾病和伤害，2）任何起源的疾病都会使人复杂 不利社会因素的负面影响。由于社会组和生物系统及其 互动，确定健康，我们的CTSA中心必须为调查人员，受训者和利益相关者提供 资源和知识以说明和解决两个系统中的健康破坏者。我们的 实施此愿景的策略是创建新的培训机制，研究平台， 通信渠道，并保护危害，以确保所有ITM调查人员和 机构以道德方式以广角社会镜头处理健康问题。然后，我们的 科学，机构和社区利益相关者可以共同设计，测试和传播生物学 和/或个人，社区和社会水平的社会指导的干预措施，以改善 相互定义的健康问题。 ITM 3.0将与整个芝加哥的合作伙伴并驾齐驱 国家，将严格的学术与社区智慧相结合，以概念化，发展和部署 创新，公正和道德的干预措施/实践，以实现我们的共同目标，从而降低健康 结构种族主义的影响。 项目摘要/摘要页面244 联系PD/PI：Solway，朱利安