Balanced and Empowered EaTing (BEET) in Diabetes: A feasibility trial

平衡与增强饮食（BEET）治疗糖尿病：可行性试验

基本信息

批准号：
10738030
负责人：
Phoutdavone Phimphasone-Brady
金额：
$ 16.98万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-01 至 2026-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10738030
关键词：
Acceleration Address Adherence Adoption Adult Affect Attitude Behavior Behavioral Behavioral Research Biological Blood Glucose Body mass index Caring Chronic Disease Clinic Clinical Clinical Trials Design Cognitive Therapy Colorado Data Data Analyses Data Collection Diabetes Mellitus Disease Disease Management Eating Eating Behavior Eating Disorders Education Educational Intervention Effectiveness Endocrine Evaluation Evidence based intervention Evidence based practice Evidence based program Exercise Fasting Future Glycosylated hemoglobin A Goals Health Health Personnel Hyperphagia Hypertriglyceridemia Individual Intake Intervention Interview K-Series Research Career Programs Laboratories Learning Skill Maintenance Measures Mediating Medical Mental Health Mentors Mentorship Metabolic Metabolic Control Methods Neuroendocrinology Non-Insulin-Dependent Diabetes Mellitus Outcome Participant Patient Outcomes Assessments Patients Persons Pharmacology Prevention approach Procedures Protocols documentation Provider Psyche structure Psychiatry Psychologist Randomized Reach, Effectiveness, Adoption, Implementation, and Maintenance Readiness Recommendation Replicating Effective Programs Reporting Research Research Training Risk Risk Factors Sample Size Self Efficacy Services Structure Surveys Training Translations Universities analytical method arm behavioral health behavioral health intervention biobehavior career comparative design diabetes distress diabetes self-management diet and exercise dissemination science effectiveness/implementation trial empowerment evidence base experience feasibility testing feasibility trial fruits and vegetables glucose monitor glycemic control high body mass index implementation evaluation implementation framework implementation science implementation strategy improved interest intervention effect member novel participant enrollment pilot test primary care clinic primary outcome professor programs recruit resilience screening self help skills treatment strategy

项目摘要

PROJECT SUMMARY Up to 20% - or nearly 7,000,000 – adults with diabetes (T2DM) concurrently experience disordered eating behaviors (DEBs, e.g., significant overeating with loss of control), resulting in higher body mass index and lower adherence to diet and exercise recommendations. DEBs are often disregarded by medical providers and patients, and therefore undertreated in clinical settings. Research is limited on whether treatment for DEBs impacts diabetes self-management and glycemic functioning. To address this, we developed the Balanced and Empowered EaTing (BEET) in Diabetes, or the BEET Diabetes Program, a novel cognitive-behavioral therapy- based program to designed to specifically treat DEBs in T2DM and improve diabetes self-management. By designing with implementation science methods and engaging integrated behavioral health providers (BHPs) in real clinical settings, we aim to 1) address an important treatment need for people with T2DM and concurrent DEBs, and 2) improve the integration of BHPs in collaborative diabetes care in clinical settings. Candidate and Mentors: I am an Assistant Professor in the Department of Psychiatry at the University of Colorado. As a clinical health psychologist with training in implementation science methods, my program of research aims to implement and evaluate evidence-based programs for mental health conditions that could worsen diabetes and other endocrinopathies. I have built a strong mentorship team to guide my training including primary mentor, Dr. C. Neill Epperson (neuroendocrinology of risk and resilience), and co-mentor, Dr. Bethany Kwan (dissemination & implementation science). Research and Training: I propose short term scientific, educational, and training goals that will build upon my prior research training through three research aims: 1) engage BHPs to refine the BEET Diabetes Program for implementation in clinical settings, 2) evaluate the feasibility of the BEET Diabetes Program, and 3) determine the reach and estimate the effectiveness of the BEET Diabetes Program on patient-reported and clinical outcomes. The complementary training goals to establish scientific independence through training in: 1) advanced mixed-methods analytical skills by learning configurational comparative methods for implementation science, 2) clinical trial design for behavioral research and longitudinal data analysis, and 3) methods for biological data collection, analysis, and interpretation in T2DM. Summary: DEBs in T2DM are a serious yet under-recognized clinical problem. There is a significant dearth of research examining associated risk factors and treatments of DEBs in T2DM. My ultimate career goal is to transform our approach to the prevention of endocrine- and metabolic-conditions by developing and implementing evidence-based mental/behavioral programs in clinical settings. Completion of this career development award will accelerate my path towards becoming a national expert in the biobehavioral management of endocrinopathies.

项目概要高达 20%（或近 7,000,000 名）成人糖尿病 (T2DM) 同时患有饮食失调行为（DEB，例如，严重暴饮暴食并失去控制），导致较高的体重指数和较低的体重指数 DEB 经常被医疗服务提供者忽视，患者，因此在临床环境中治疗不足的研究仅限于 DEB 的治疗。影响糖尿病的自我管理和血糖功能为了解决这个问题，我们开发了平衡和血糖功能。糖尿病赋权饮食（BEET），或 BEET 糖尿病计划，一种新型认知行为疗法 - 旨在专门治疗 T2DM 中的 DEB 并改善糖尿病自我管理的计划。采用实施科学方法进行设计并让综合行为健康提供者 (BHP) 参与在真实的临床环境中，我们的目标是 1) 满足 T2DM 患者和并发患者的重要治疗需求 DEB，2) 改善 BHP 在临床环境中糖尿病协作护理中的整合。候选人和导师：我是纽约大学精神病学系的助理教授科罗拉多州，作为一名接受过实施科学方法培训的临床健康心理学家，我的计划是研究旨在实施和评估针对心理健康状况的循证计划，这些计划可以我建立了一个强大的指导团队来指导我的培训，包括恶化的糖尿病和其他内分泌疾病。主要导师 C. Neill Epperson 博士（风险和复原力神经内分泌学）和共同导师 Bethany 博士 Kwan（传播与实施科学）。研究和培训：我提出短期科学、教育和培训目标，这些目标将建立在我的基础上通过三个研究目标进行前期研究培训：1) 让 BHP 完善 BEET 糖尿病计划在临床环境中实施，2) 评估 BEET 糖尿病计划的可行性，以及 3) 确定 BEET 糖尿病计划对患者报告和临床的影响范围和有效性评估通过以下方面的培训建立科学独立性的补充培训目标：1) 通过学习实施的配置比较方法来提高混合方法分析技能科学，2）行为研究和纵向数据分析的临床试验设计，以及 3）方法 T2DM 中的生物学数据收集、分析和解释。摘要：T2DM 中的 DEB 是一个严重但未被充分认识的临床问题。研究检查 T2DM 中 DEB 的相关风险因素和治疗方法我的最终职业目标是通过开发和改进我们预防内分泌和代谢疾病的方法在临床环境中实施基于证据的心理/行为计划。发展奖将加速我成为国家生物行为专家的道路内分泌疾病的管理。