LEAP Administrative Core

LEAP 管理核心

基本信息

批准号：
10623803
负责人：
Dost Ongur
金额：
$ 48.38万
依托单位：
MCLEAN HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-05-15 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10623803
关键词：
Administrator Advocacy Agreement Area Authorship Boston Budgets Clinic Clinical Clinical Data Collaborations Communication Community Outreach Comparative Effectiveness Research Coordinated Specialty Care Data Data Collection Data Science Data Set Dedications Development Discipline Elements Ensure Epidemiology Evaluation Faculty Family Fostering Funding Goals Health Policy Health Services Research Heterogeneity Hospitals Hybrids Incubators Industry Institutional Review Boards Intervention Laboratories Lead Location Maintenance Manuscripts Massachusetts Medicine Mental Health Methods Modernization Monitor National Institute of Mental Health Nature Occupations Patient-Focused Outcomes Patients Performance Persons Pilot Projects Policies Policy Maker Process Progress Reports Psychiatry Psychology Randomized, Controlled Trials Reporting Research Research Personnel Research Project Grants Resources Rotation Schedule Science Series Services Site Social Work Strategic Planning Structure Sum Testing Training Training Programs Training Support Twitter Work catalyst data access data management data standards data submission design early psychosis first episode psychosis interdisciplinary collaboration laboratory experiment meetings multimodality programs statistics symposium synergism tool training opportunity training project treatment effect virtual visiting scholar web site

项目摘要

Abstract The Administrative Core for the “Laboratory in Early Psychosis” Center, a.k.a. LEAP Center, will support continued activities of the currently existing Center. This involves the research consortium of first episode psychosis clinics in Massachusetts and an interdisciplinary team of leading researchers. The LEAP Center is dedicated to research in first episode psychosis, including testing an intervention strategy in our consortium of clinics in a randomized controlled trial, extensive multimodal longitudinal data collection, and prediction and comparative effectiveness research using various clinical datasets to better understand heterogeneity in patient outcomes and treatment impacts. The Administrative Core will serve the Center’s goals by facilitating regular communication, fostering synergy among disciplines, supporting training opportunities and pilot projects, disseminating information on Center activities, organizing stakeholder panels, and overseeing evaluation of the Center itself. The Core will be led by the Center Leads Drs. Öngür, Hsu, and Hernan, and supported by a Center Administrator. It will be housed in dedicated office space at McLean Hospital. The Core has four aims. First, it will oversee and coordinate all activities essential to the functioning of the Center, including maintenance of regulatory and contractual obligations, management of budgets and subcontracts, interacting with academic, state, and federal agencies, completion of reporting requirements, supporting regular communication between Center elements, and fostering and tracking collaborations. Second, the Core will oversee and coordinate governance structures including the Steering, Manuscript, Data Management and Access, Pilot Project, and Training committees within the Center. Third, it will manage the solicitation, review, funding, monitoring, and reporting of the conduct of an average of two R03-level pilot projects each year. And fourth, the Administrative Core will coordinate and manage engagement with a diverse array of stakeholders including patient and family groups, national and state policy makers, payers, as well as a panel of senior scientific experts. The Core will also support dissemination of Center activities and advances through conferences and short courses, visiting scholar series, clinical case conferences, as well as a website. Finally, the Administrative Core will track objective metrics of Center performance and convene annual meetings of the Advisory Board (composed of senior investigators within and outside of psychiatry research which will conduct assessments of Center progress and suggest refinements). Taken together, the Core activities are designed to ensure that the LEAP Center remains a unified whole that is greater than the sum of its parts.

抽象的 “早期精神病实验室”中心（又名 LEAP 中心）的行政核心将支持当前现有中心的继续活动这涉及第一集的研究联盟。马萨诸塞州的精神病诊所和一个由领先研究人员组成的跨学科团队。致力于研究首发精神病，包括在我们的联盟中测试干预策略临床随机对照试验、多模式纵向数据收集以及预测和使用各种临床数据集进行比较有效性研究，以更好地了解异质性行政核心将通过促进患者的结果和治疗的影响来服务于中心的目标。定期沟通，促进学科间的协同，支持培训机会和试点项目、传播有关中心活动的信息、组织利益相关者小组并监督中心本身的评估将由中心领导 Öngür、Hsu 和 Hernan 博士领导。该中心将由中心管理员提供支持，位于麦克莱恩医院的专用办公空间内。首先，它将监督和协调对中心运作至关重要的所有活动，包括维持监管和合同义务、预算和分包合同的管理，与学术、州和联邦机构互动，完成报告要求，支持第二，中心要素之间的定期沟通，并促进和跟踪合作。将监督和协调治理结构，包括指导、手稿、数据管理和中心内的准入、试点项目和培训委员会第三，它将管理征集、审查、每年平均资助、监测和报告两个 R03 级试点项目的实施情况。第四，行政核心将协调和管理与不同利益相关者的互动包括患者和家庭团体、国家和州政策制定者、付款人以及老年人小组核心还将通过以下方式支持中心活动和进展的传播。会议和短期课程、访问学者系列、临床病例会议以及网站。行政核心将跟踪中心绩效的客观指标并召开年度会议咨询委员会（由精神病学研究内外的高级研究人员组成，将进行总而言之，核心活动旨在：确保 LEAP 中心始终是一个大于各个部分之和的统一整体。