LEAP Administrative Core

LEAP 管理核心

基本信息

批准号：
10376217
负责人：
Dost Ongur
金额：
$ 104.39万
依托单位：
MCLEAN HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-05-15 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10376217
关键词：
Administrator Advocacy Agreement Area Authorship Boston Budgets Caring Clinic Clinical Clinical Research Collaborations Communication Community Outreach Comparative Effectiveness Research Computer software Data Data Analyses Data Collection Data Science Development Discipline Elements Ensure Epidemiology Evaluation Faculty Faculty Workshop Family Fostering Funding General Population Goals Health Policy Health Services Research Health system Healthcare Systems Heterogeneity Hospitals Incubators Industry Information Systems Institutes Institutional Review Boards Laboratories Lead Learning Location Maintenance Manuscripts Massachusetts Medicine Mental Health Methods Modernization Monitor National Institute of Mental Health Participant Patient-Focused Outcomes Patients Performance Persons Pilot Projects Policies Policy Maker Process Progress Reports Protocols documentation Psychiatry Psychology Reporting Research Research Activity Research Personnel Research Project Grants Resources Schedule Science Series Services Social Work Structure Suicide prevention Sum Training Training Programs Training Support Translational Research Work biobank catalyst clinical practice clinical translation data access data management data sharing design digital digital communication early psychosis first episode psychosis improved interdisciplinary collaboration intervention program lectures medical specialties meetings multimodality phenotypic data programs statistics symposium synergism tool training opportunity treatment effect visiting scholar web site webinar

项目摘要

1. Abstract The Administrative Core for the “Laboratory in Early Psychosis” Center, a.k.a. LEAP, will support the creation of a research consortium spanning three major first episode psychosis clinics in Massachusetts and the formation of a transdisciplinary team of leading researchers. The LEAP Center is dedicated to T2 translational research in first episode psychosis, including analysis of the impact of specialized care, extensive multimodal longitudinal data collection, and prediction and comparative effectiveness research to better understand heterogeneity in patient outcomes and treatment effects. The Administrative Core will serve the Center’s goals by facilitating regular communication, fostering synergy among disciplines, supporting training opportunities and pilot projects, disseminating information on Center activities, organizing stakeholder panels, and overseeing evaluation of the Center itself. The Core will be led by the Center Leads Drs. Öngür, Hsu, and Hernan, and supported by a Center Administrator. The Core has four aims. First, it will oversee and coordinate all activities essential to the functioning of the Center, including maintenance of regulatory and contractual obligations, management of budgets and subcontracts, interacting with academic, state, and federal agencies, completion of reporting requirements, supporting regular communication between Center elements, and fostering and tracking collaborations. Second, the Core will oversee and coordinate governance structures including the Steering, Manuscript, Data Management and Access, Pilot Project, and Training committees within the Center. Third, it will manage the solicitation, review, funding, monitoring, and reporting of the conduct of an average of two R03-level pilot projects each year. And fourth, the Administrative Core will coordinate and manage engagement with a diverse array of stakeholders including patient and family groups, national and state policy makers, payers, as well as a panel of senior scientific experts. The Core will also support dissemination of Center activities and advances through conferences and short courses, visiting scholar series, clinical case conferences, protocols and software, as well as a website intended to serve the general public. Finally, the Administrative Core will track objective metrics of Center performance and convene annual meetings of the Advisory Board (composed of senior investigators within and outside of psychiatry research which will conduct assessments of Center progress and suggest refinements) as well as convene regular meetings of the Center’s Faculty Panel, and Stakeholder Committees. Taken together, the Core activities are designed to ensure that the LEAP Center becomes a unified whole that is greater than the sum of its parts.

1.摘要 “早期精神病实验室”中心（又名 LEAP）的行政核心将支持创建一个研究联盟的成员，该联盟涵盖马萨诸塞州和美国三个主要的首发精神病诊所 LEAP 中心组建了一支由领先研究人员组成的跨学科团队，致力于 T2 转化。首发精神病的研究，包括分析专业护理、广泛的多模式的影响纵向数据收集、预测和比较有效性研究，以更好地了解患者结果和治疗效果的异质性将服务于中心的目标。通过促进定期沟通、促进学科之间的协同作用、支持培训机会和试点项目，传播有关中心活动的信息，组织利益相关者小组，以及核心部门将由中心领导 Öngür、Hsu 和 Drs 领导。埃尔南在中心管理员的支持下有四个目标：首先，它将进行监督和协调。对中心运作至关重要的所有活动，包括维护监管和合同义务、预算和分包合同的管理、与学术、州和联邦机构的互动，完成报告要求，支持中心各部门之间的定期沟通，以及其次，核心将监督和协调治理结构。包括指导委员会、手稿委员会、数据管理和访问委员会、试点项目委员会和培训委员会第三，它将管理该行为的征集、审查、资助、监控和报告。平均每年有两个 R03 级试点项目。第四，行政核心将协调和实施。管理与不同利益相关者的参与，包括患者和家庭团体、国家和国家政策制定者、付款人以及高级科学专家小组也将提供支持。通过会议和短期课程、访问学者系列传播中心的活动和进展，临床病例会议、协议和软件，以及旨在为公众服务的网站。最后，行政核心将跟踪中心绩效的客观指标并召开年度会议咨询委员会会议（由精神病学研究内外的高级研究人员组成）将对中心进展进行评估并提出改进建议）并定期召开会议该中心的教师小组和利益相关者委员会的会议，核心活动是。旨在确保 LEAP 中心成为一个大于各个部分之和的统一整体。