Transdisciplinary Training In Cardiovascular Research

心血管研究的跨学科培训

• 批准号: 10270065
• 负责人: J Kevin Donahue
• 金额: $ 53.35万
• 依托单位: UNIV OF MASSACHUSETTS MED SCH WORCESTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10270065
• 关键词: Cardiovascular system; Research; Training

ABSTRACT We propose the 1st competitive renewal of our transdisciplinary cardiovascular sciences training program (CVT32) at the University of Massachusetts Medical School (UMMS). We will continue to encompass the full spectrum of cardiovascular (CV) research from basic to population health. This breadth is part of the UMMS culture of conducting science that makes a difference. The CVT32 is a collaboration between the Division of Cardiovascular Medicine in the Department of Medicine and the Department of Population and Quantitative Health Sciences (PQHS) and involves 48 participating faculty from multiple departments. Our two MPIs have different research expertise, with one (Freedman) more in the bench through phase 1 clinical trials arena and the other (Kiefe) in the phase 2/3 clinical trials (efficacy) through effectiveness, implementation, and population-sciences arena. Trainees will have mentoring teams with a lead mentor in their CV area of interest and a co-mentor plus an additional mentor-in-training representing very different areas of research. The synergism of our CVT32 faculty spanning the entire spectrum is a unique strength of our CVT32 enabling us to train scientists in a transdisciplinary way, with bidirectional hypothesis generation. Team mentoring and hands-on research experience through the entire training period are key components of our CVT32, together with structured coursework and abundant enrichment activities tailored to the individual trainee. We have a doctoral program and a Masters of Science of Clinical investigation housed in PQHS, where all CVT32 trainees will each have their own cubicle, in close physical proximity to researchers across the spectrum. Building on the success of our 1st funding period, we propose to enlarge the program by attaining a steady-state of 4 postdoctoral trainees and 4 predoctoral trainees at a time, with terms of 2-3 years; and newly adding a 12-week summer research training experiences for 8 medical students/year enrolled in a 4-year clinical and translational research pathway. Thus, our aims are to 1) Expand our successful CVT32 across basic, clinical, and population health sciences geared towards translating research into effective clinical practice and policy, and generating new questions spanning the entire spectrum of CV research. 2) Recruit pre-and post- doctoral trainees forming a diverse group regarding sociodemographics, clinical background, and disciplinary perspectives. 3) Provide trainees with the individual mentoring, academic training, and technical skills that will ensure their success as independent investigators as well as contributors to team science. 4) Provide “hands on” research experiences within transdisciplinary teams that build on the strengths of the current environment of linkages between UMMS Departments, Centers, and Institutes.

抽象的 我们提议对我们的跨学科心血管科学培训进行第一次竞争性更新 我们将继续在马萨诸塞大学医学院 (UMMS) 开展计划 (CVT32)。 涵盖从基础到人口健康的全方位心血管（CV）研究。 是 UMMS 开展科学文化的一部分，CVT32 是一种合作。 医学系心血管内科与医学系之间 人口与定量健康科学 (PQHS)，涉及来自多个国家的 48 名参与教师 部门。 我们的两个 MPI 拥有不同的研究专长，其中还有一名（Freedman）在替补席上 1期临床试验（Kiefe）在2/3期临床试验（疗效）通过 有效性、实施和人口科学领域将有指导团队。 在他们感兴趣的简历领域有一名首席导师和一名共同导师以及一名额外的培训导师 代表了我们 CVT32 整个研究领域的协同作用。 频谱是我们 CVT32 的独特优势，使我们能够以跨学科的方式培训科学家， 具有双向假设生成的团队指导和实践研究经验。 整个培训期间以及结构化课程作业和 为每位学员量身定制丰富的丰富活动 我们有一个博士课程和一个博士课程。 临床研究理学硕士课程位于 PQHS，所有 CVT32 学员将分别获得 他们自己的小隔间，与各个领域的研究人员在物理上非常接近。 在我们第一个资助期取得成功的基础上，我们建议通过实现 稳定状态，每次4名博士后和4名博士前，任期2-3年； 并新增每年8名医学生为期12周的暑期科研训练经历 参加了为期 4 年的临床和转化研究途径。 因此，我们的目标是 1) 将我们成功的 CVT32 扩展到基础、临床和人口健康领域 科学致力于将研究转化为有效的临床实践和政策，并产生 涵盖整个简历研究领域的新问题 2) 招募博士前和博士后实习生。 形成一个关于社会人口统计学、临床背景和学科的多元化群体 3) 为学员​​提供个人指导、学术培训和技术技能。 这将确保他们作为独立研究者和团队科学的贡献者取得成功 4)。 在跨学科团队中提供“实践”研究经验，这些经验建立在跨学科团队的优势之上 UMMS 各系、中心和研究所之间当前的联系环境。