UCSF Nutrition Obesity Research Center

加州大学旧金山分校营养肥胖研究中心

• 批准号: 9118181
• 负责人: CHRISTIAN VAISSE
• 金额: $ 118.85万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9118181
• 关键词: Animals; Area; Basic Science; Behavioral; Biomedical Research; California; Clinical; Clinical Research; Collaborations; Communities; Development; Direct Costs; Disease; Ensure; Epidemiology; Equipment; Evolution; Funding; Genetic; Genomics; Goals; Grant; Growth; Human; Image; Laboratories; Lead; Leadership; Link; Maintenance; Measures; Metabolic Diseases; Metabolism; Modification; Mus; National Institute of Diabetes and Digestive and Kidney Diseases; Nutritional Study; Nutritionist; Obesity; Prevention; Principal Investigator; Process; Research; Research Infrastructure; Research Personnel; Research Support; Resources; San Francisco; Schools; Scientist; Seeds; Series; Services; Staging; System; Technology; Tissues; Training; Training Programs; United States National Institutes of Health; Universities; base; improved; improved outcome; innovation; meetings; member; metabolic abnormality assessment; mouse genome; nutrition; obesity treatment; programs; public health relevance; radiologist

 DESCRIPTION (provided by applicant): The proposed UCSF NORC will integrate multiple research programs in multiple areas of nutrition, obesity and metabolism. Over the last twelve years, UCSF has actively expanded its research base in this critical subject area. Today, that research base is very robust but with an administrative and facilities infrastructure that reflects the diversity of the departmental processes that expanded this program. The proposed NORC will provide a cohesive programmatic, administrative and shared facilities infrastructure that will integrate the already strong nutrition, obesity and metabolism research conducted at UCSF and that will provide a framework for its coordinated growth. The UCSF NORC will include cellular, animal, translational, clinical and epidemiologic directions. Despite this breath, these programs are highly interactive with extensive collaborations amongst even the most divergent of programs. For example, radiologists collaborate with clinical scientists to non-invasively visualize metabolism in humans. Human geneticists collaborate with cellular and animal researchers to investigate hypotheses more tractable in those systems. Behavioral scientists coordinate with nutritionists to search for ways to improve outcomes. In all, the 44 interdisciplinary investigators within the UCSF-NORC will consist of a mixture of senior and early stage investigators with a collective 60 NIH grants (100 grants total). Their collective goal will be to define the underlying mechanisms of disease and to significantly contribute to the prevention and treatment of obesity and its complications. The purpose of the UCSF-NORC will be to promote and grow research in obesity, nutrition, and metabolism at UCSF and throughout northern California. This will be realized by: Maintaining, improving, and promoting the interactions and collaborations of researchers in the field with each other and with those outside the field. Supporting the maintenance and evolution of state-of-the-art Research Cores to meet the needs of obesity, nutrition, and metabolism research. Facilitating the development of new research directions and the entry of new researchers into the field via Pilot & Feasibility opportunities. Enriching the NORC research community through pertinent educational forums and other venues that support the development and maintenance of research interactions. Integrating administrative support to ensure that the infrastructure meets the needs of the local obesity, nutrition and metabolism research community.

 描述（由适用提供）：拟议的UCSF NORC将在营养，肥胖和代谢的多个领域中整合多个研究计划。在过去的十二年中，UCSF积极扩大了在这个关键主题领域的研究基础。如今，该研究基础非常强大，但具有反映的行政和设施基础架构 扩大该计划的部门流程的多样性。拟议的NORC将提供一个具有凝聚力的程序化，行政和共享设施基础架构 整合了在UCSF进行的已经强大的营养，肥胖和代谢研究，并将为其协调增长提供框架。 UCSF NORC将包括细胞，动物，翻译，临床和流行病学方向。尽管有这种呼吸，但这些程序与最不同的程序之间的广泛合作具有高度互动性。例如，放射科医生与临床科学家合作，非侵入性地可视化人类的新陈代谢。人类遗传学家与细胞和动物研究人员合作研究了这些系统中更可探讨的假设。行为科学家与营养学家协调，以寻找改善结果的方法。总而言之，UCSF-NORC中的44位跨学科研究人员将由高级和早期研究人员组成，并拥有60个NIH赠款（总计100赠款）。他们的集体目标 将定义疾病的潜在机制，并显着有助于预防和治疗肥胖及其并发症。 UCSF-NORC的目的是在UCSF以及整个加利福尼亚州促进和发展有关肥胖，营养和代谢的研究。这将通过：维持，改善和促进该领域研究人员以及与该领域外的研究人员的互动和协作。支持最先进的研究核心的维护和演变，以满足观察，营养和代谢研究的需求。通过飞行员和可行性机会促进新研究方向的发展以及新研究人员进入该领域。通过相关的教育论坛和其他支持研究互动的发展和维护的场所来丰富NORC研究社区。整合行政支持，以确保基础设施满足当地肥胖，营养和代谢研究界的需求。