COG NCORP Research Base

COG NCORP研究基地

基本信息

批准号：
9116795
负责人：
BRAD H POLLOCK
金额：
$ 323.12万
依托单位：
CHILDREN'S HOSP OF PHILADELPHIA
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-08-01 至 2019-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9116795
关键词：
Address Adolescent Adolescent and Young Adult Adult Adverse effects Affect Aftercare American Australia Cancer Center Cancer Control Cancer Etiology Caring Characteristics Child Childhood Clinical Medicine Clinical Research Clinical Trials Collaborations Communities Community Clinical Oncology Program Community Participation Data Quality Dose Ensure Ethnic group Europe Funding Goals Gynecologic Oncology Group Health Health Professional Human Resources Human Subject Research Information Management Institution Interdisciplinary Study Intervention Laboratories Laboratory Research Malignant Childhood Neoplasm Malignant Neoplasms Minority Mission Monitor New Zealand North America Operative Surgical Procedures Outcome Pathology Patients Pediatric Hospitals Pediatric Oncologist Pediatric Oncology Pediatric Oncology Group Pediatric Research Persons Positioning Attribute Prevention strategy Protocols documentation Provider Quality of life Race Radiation Oncology Research Research Infrastructure Research Personnel Resources Site Symptoms System Therapeutic Training Support Translating Treatment Protocols Underserved Population Universities anticancer research base cancer care cancer prevention cancer therapy care delivery community setting data management design effective therapy follow-up health care delivery health care service organization health related quality of life improved improved outcome meetings member novel therapeutic intervention patient population prevent programs quality assurance survivorship underserved minority

项目摘要

DESCRIPTION (provided by applicant): The Children's Oncology Group (COG) is the largest childhood cancer research organization in the world encompassing 224 pediatric cancer programs with a mission to cure and prevent childhood and adolescent cancer through scientific discovery and compassionate care. GOG was formed from the merger of four legacy pediatric cooperative groups in 2000 and the COG Community Clinical Oncology Program (CCOP) Research Base was funded in 2002. The proposed COG NCORP Research Base will support 25 Community Sites and 12 Minority/Underserved Community Sites and is the only research base exclusively dedicated to children and adolescents. It will encompass the near totality of U.S. community pediatric oncology. The COG NCORP Research Base will provide access to state-of-the-art cancer treatment at community sites and nationally promote pediatric research in cancer prevention and control, post-treatment surveillance/survivorship, and cancer care delivery. COG trials and laboratory research will translate into more effective treatments with reduced side effects. Community-based pediatric oncologists and other health professionals are pivotal to COG's research mission. NCORP sites provide a means to evaluate advanced treatments administered in community settings. The COG makes available to NCORP sites current treatment protocols with access to investigational agents and special centralized reference laboratories, continuing training and support for NCORP personnel, quality assurance infrastructure, data management and statistical support, thus promoting scientific discovery and high quality cancer care for young persons. The COG is uniquely positioned to elucidate the impact of different health care delivery systems and characteristics on cancer outcomes and identify determinants of poorer outcomes in certain race/ethnic and underserved groups such as adolescents and young adults. Such research will improve outcomes by eliminating disparities and improving efficiencies for the delivery of cancer therapy and follow-up care in young persons.

描述（由申请人提供）：儿童肿瘤学组（COG）是世界上最大的儿童癌症研究组织，其中包括224个小儿癌症计划，其使命是通过科学发现和富有同情心的护理来治愈和预防儿童和青少年癌症。 GOG是由2000年四个传统儿科合作团体的合并形成的，COG社区临床肿瘤学计划（CCOP）研究基础于2002年资助。拟议的COG NCORP研究基础将支持25个社区站点和12个少数群体/不足的社区站点，并且是唯一专门专门专门致力于儿童和教会的研究基础。它将涵盖大量的美国社区小儿肿瘤学。 COG NCORP研究基础将在社区场所提供最先进的癌症治疗，并在全国范围内促进预防癌症预防和控制，治疗后监视/生存和癌症护理的小儿研究。 COG试验和实验室研究将转化为副作用减少的更有效的治疗方法。基于社区的儿科肿瘤学家和其他卫生专业人员对COG的研究任务至关重要。 NCORP站点提供了一种评估社区环境中管理的高级治疗方法的方法。该COG可向NCORP站点提供当前的治疗方案，该方案可以使用研究代理和特殊的集中参考实验室，继续对NCORP人员进行培训和支持，质量保证基础设施，数据管理和统计支持，从而促进了对年轻人的科学发现和高质量的癌症护理。 COG具有独特的位置，以阐明不同的医疗保健提供系统和特征对癌症结果的影响，并确定某些种族/种族和服务不足的群体（例如青少年和年轻人）中较差结果的决定因素。这样的研究将通过消除差异和提高癌症治疗和年轻人的随访效率来改善结果。