Multi-Component Behavioral Activation, Nutrition, and Activity Intervention for Persons Aging with HIV

针对老年艾滋病毒感染者的多成分行为激活、营养和活动干预

• 批准号: 10612576
• 负责人: ANN L GRUBER-BALDINI
• 金额: $ 40.22万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10612576
• 关键词: Address; Administrative Supplement; Aerobic; Age; Aging; Anxiety; Area; Attention; Baltimore; Behavior; Behavior Therapy; Behavioral; Cardiovascular Diseases; Chronic; Chronic Disease; Clinic; Clinical; Clinical Research; Communities; Diabetes Mellitus; Disease Progression; Elderly; Evaluation; Exercise; Feasibility Studies; Feedback; Female; Focus Groups; Fostering; HIV; HIV Infections; HIV diagnosis; Health; Health Promotion; Health behavior; Healthy Eating; Home; Homes for the Aged; Hypertension; Interval training; Intervention; Intervention Studies; Kidney Diseases; Life Style; Liver diseases; Loneliness; Malignant Neoplasms; Measures; Meditation; Mental Depression; Modeling; Morbidity - disease rate; Motivation; Muscular Atrophy; Nature; Nutritional; Outcome; Pamphlets; Participant; Patients; Persons; Phase; Physical activity; Population; Problem Solving; Provider; Quality of life; Rehabilitation therapy; Reporting; Research; Research Personnel; Resources; Rewards; Risk; Sampling; Schedule; Social isolation; Social support; Structure; Symptoms; Tablets; Telephone; Time; Translating; Underrepresented Minority; United States; Vulnerable Populations; Walking; Work; acceptability and feasibility; aged; antiretroviral therapy; base; clinical center; community center; community engagement; community setting; coronavirus disease; depressive symptoms; design; disability; efficacy trial; falls; feasibility testing; frailty; functional disability; implementation intervention; improved; improved functioning; intervention effect; novel; nutrition; pilot test; preference; programs; psychologic; psychosocial; recruit; remote delivery; sarcopenia; social; social engagement; social stigma; telecoaching; translational potential; willingness

Summary This administrative supplement will test the feasibility and acceptability of a brief (12 week) individualized, Behavioral Activation program focused on decreasing loneliness and increasing social engagement, that will be augmented with a program to increase home exercise and address poor nutrition among persons aging with HIV. It will be delivered by remote coaches. Recruitment will include those ages 50+ with HIV from the UM THRIVE program and other HIV centers in Baltimore as necessary. This work will be accomplished in three stages: Stage 1: We will start with community engagement strategies, such as focus groups with persons aging with a HIV diagnosis and clinical providers, to tailor the intervention. A community engagement team will provide feedback on preferences for delivery mode (telephone, tablet, home, and/or at a community center), recruitment strategies and brochures, measures, other study materials, inclusion of the physical activity and nutrition modules. Stage 2: We will work with HIV clinical and research experts in exercise, nutrition, and psychological functioning to tailor the content of the material and resources for the remote coaches in order to meet the needs of PAWH. Stage 3: Following the community engagement and tailoring the intervention for PAWH, we will pilot test feasibility acceptability with 10 persons ages 50+ living with a HIV diagnosis. This study will test the feasibility of a much-needed intervention to improve functioning and health outcomes among a vulnerable group of older adults. It is a single-group unblinded feasibility study to explore a new intervention to support older people aging with HIV. If this intervention appears to be feasible, acceptable, and to show preliminary evidence of efficacy, we will look be to evaluate it in a phase III efficacy trial. It fits into the scope of the UM-OAIC, which aims to conduct research on the mechanisms that underly the functional impairments associated with prevalent chronic diseases in older people; design novel, efficacious rehabilitation interventions; and translate interventions for implementation and rigorous evaluation outside the clinic (e.g., home, senior center, gym).

概括 该行政补充文件将测试短期（12 周）个性化的可行性和可接受性， 行为激活计划的重点是减少孤独感和增加社交参与度，这将 加强一项计划，以增加家庭锻炼并解决老年痴呆症患者的营养不良问题 艾滋病病毒。它将由远程教练提供。招募的对象将包括来自 UM 的 50 岁以上艾滋病病毒感染者 必要时，繁荣计划和巴尔的摩的其他艾滋病毒中心。这项工作将分三期完成 阶段：第一阶段：我们将从社区参与策略开始，例如与人员进行焦点小组 与艾滋病毒诊断和临床提供者一起老龄化，以定制干预措施。社区参与团队将 提供有关交付模式偏好的反馈（电话、平板电脑、家庭和/或社区中心）， 招聘策略和宣传册、措施、其他学习材料、体育活动和 营养模块。第二阶段：我们将与艾滋病毒临床和研究专家在运动、营养和治疗方面合作 心理功能，为远程教练量身定制材料和资源的内容，以便 满足PAWH的需求。第三阶段：遵循社区参与并定制干预措施 PAWH，我们将对 10 名 50 岁以上患有艾滋病毒诊断的人进行试点测试可行性可接受性。这 研究将测试一项急需的干预措施的可行性，以改善患者的功能和健康结果 老年人的弱势群体。这是一项单组非盲可行性研究，旨在探索新的干预措施 支持感染艾滋病毒的老年人。如果这种干预措施看起来可行、可接受并表明 初步的疗效证据，我们将在 III 期疗效试验中对其进行评估。它符合范围 UM-OAIC，旨在研究功能障碍的机制 与老年人流行的慢性疾病有关；设计新颖，康复有效 干预措施；并将干预措施转化为临床外的实施和严格评估（例如， 家、老年中心、健身房）。