Training In Cardiovascular Physiology & Pharmacology

心血管生理学培训

• 批准号: 9098764
• 负责人: Robert Scott Ross
• 金额: $ 48.95万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1979
• 资助国家: 美国
• 起止时间: 1979-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9098764
• 关键词: Cardiovascular Physiology; Training; cardiovascular pharmacology

DESCRIPTION (provided by applicant): This proposal is for a long-standing, comprehensive, multidisciplinary program to train cardiovascular scientists in mechanisms of disease, and means to develop novel diagnostic and therapeutic approaches to cardiovascular illnesses. It focuses on the use of cellular, molecular, pharmacologic, physiologic and bioengineering approaches. The range of scientific disciplines in the training plan includes: 1) myocyte signaling and cell death, 2) cardiac development and regeneration, 3) the role of the extrasarcomeric cytoskeleton in cardiomyopathy, and 4) cardiac bioengineering. The proposal aims to continue with 2 pre-doctoral and 6 post-doctoral positions each year. The pre-doctoral training positions will draw from some of the best of a group of excellent students in the University of California, San Diego (UCSD) Biomedical Sciences, Bioengineering, and Medical Scientist Training (MSTP) programs. The postdoctoral positions are drawn from a large pool of Ph.D. postdoctoral fellows at UCSD, a Physician-Scientist Training Program (PSTP) in the Department of Medicine, and select cardiology fellows who demonstrate a strong interest in pursuing a career in cardiovascular science. The program aims to groom the trainees in acquisition of the knowledge and skills necessary to become independent investigators in cardiovascular research. At least two years of training will be required of all postdoctoral trainees. The Faculty of the program are from the Departments of Medicine, Pharmacology, Anesthesiology, School of Pharmacy and Bioengineering at UCSD and draw from the resources of the School of Medicine, School of Engineering, the Institute of Engineering in Medicine, the Cardiac Biological Science and Engineering Center, the new Sulpizio Cardiovascular Center, the Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Veterans Affairs Medical Center. The program has both didactic and laboratory experiences. Most trainees will be cross-trained in several disciplines. Thoughtful career guidance will be a component of all stages of the program. Importantly, the training program will be tailored to meet each individual's specific long-term goals, to equip them best for a successful future in academic medicine and research. 117 trainees have received support from this training program since its inception in 1978. Almost 50% now hold positions as academic faculty with several serving in or having served in leadership positions. Another 30% have scientific positions in the biotechnology industry. Over the last 10 years, 81% of former trainees have continued to actively publish original work in journals cited by PubMed. This proposal will facilitate the continued pattern of success that has been established over the years. (End of Abstract)

描述（由申请人提供）：该提案是一项长期、全面、多学科的计划，旨在培训心血管科学家了解疾病机制，并开发针对心血管疾病的新型诊断和治疗方法。它侧重于细胞、分子、药理学、生理学和生物工程方法的使用。培训计划中的科学学科范围包括：1）肌细胞信号传导 和细胞死亡，2）心脏发育和再生，3）肌瘤外细胞骨架在心肌病中的作用，以及4）心脏生物工程。该提案旨在继续每年设立2个博士前职位和6个博士后职位。博士前培训职位将从加州大学圣地亚哥分校 (UCSD) 生物医学科学、生物工程和医学科学家培训 (MSTP) 项目的优秀学生中选拔。博士后职位是从大量的博士中选拔出来的。加州大学圣地亚哥分校的博士后研究员、医学系的医师科学家培训计划 (PSTP) 以及精选的对从事心血管科学职业表现出浓厚兴趣的心脏病学研究员。该计划旨在培养学员获得成为心血管研究独立研究者所需的知识和技能。所有博士后培训生至少需要接受两年的培训。该计划的学院是 来自加州大学圣地亚哥分校医学、药理学、麻醉学、药学和生物工程学院的系，并借鉴了医学院、工程学院、医学工程研究所、心脏生物科学与工程中心、新 Sulpizio 的资源心血管中心、斯卡格斯药学和药物科学学院以及退伍军人事务部医疗中心。该计划既有教学经验又有实验室经验。大多数学员将接受多个学科的交叉培训。周到的职业指导将成为该计划所有阶段的组成部分。重要的是，培训计划将根据每个人的具体长期目标量身定制，为他们在学术医学和研究领域的成功未来做好准备。自 1978 年启动以来，已有 117 名学员获得了该培训计划的支持。近 50% 的学员现在担任学术教师，其中一些人担任或曾经担任过领导职务。另外 30% 在生物技术行业拥有科学职位。过去 10 年里，81% 的前学员继续积极在 PubMed 引用的期刊上发表原创作品。该提案将促进多年来建立的持续成功模式。 （摘要完）