Informing treatment adaptation based on the interplay between behavioral undercontrol and context: an event-level study

根据行为失控和环境之间的相互作用来告知治疗适应：一项事件级研究

基本信息

批准号：
10237212
负责人：
Tim Janssen
金额：
$ 18.07万
依托单位：
BROWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-01 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10237212
关键词：
Acute Adolescent Adolescent Development Adult Affect Age Alcohol abuse Alcohol consumption Alcohols Assessment tool Behavior assessment Behavioral Characteristics Collection Complement Coupled Data Development Development Plans Ecological momentary assessment Environment Environmental Risk Factor Esthesia Etiology Event Female Adolescents Funding Future Gender Grain Health Heavy Drinking Human Impulsivity Individual Individual Differences Intervention Laboratories Laboratory Study Learning Life Link Location Male Adolescents Measures Mediating Mediation Mediator of activation protein Methods Modeling National Institute on Alcohol Abuse and Alcoholism Onset of illness Participant Patient Self-Report Pattern Persons Predisposition Process Reporting Research Role Secure Social Environment Supervision Surveys Technology Teenagers Testing Time Training United States Variant Violence Youth adolescent alcohol misuse alcohol availability alcohol consequences alcohol measurement alcohol related consequences alcohol risk alcohol use disorder base binge drinking career development computerized contextual factors design discounting drinking drinking behavior early drinking experience indexing individual variation legal drinking age mindfulness multilevel analysis peer prototype public health relevance recruit response sex social theories trait underage drinker underage drinking vehicular accident willingness

项目摘要

PROJECT SUMMARY Underage drinking in the United States is a serious health concern, with a multifaceted etiology and wide- ranging implications including risky situations (motor vehicle accidents, risky sex, and violence) and alcohol use disorder (adolescents have the highest rate of alcohol use disorder onset). Both environmental and individual characteristics are implicated in the development of adolescent drinking behavior. At the environmental level, social, locational, and situational context characteristics influence adolescent patterns of drinking. At the individual level, one of the strongest individual predictors of underage drinking is behavioral undercontrol (BU; e.g. impulsivity, sensation seeking). Interventions that target differences in BU successfully delay onset and reduce quantity of alcohol use in underage drinkers. However, research has shown that context characteristics, and differences in BU, meaningfully change drinking behavior. Hence, there is an opportunity to investigate how context effects differ by sex and are moderated by BU to produce heavy episodic drinking at the event level; by conducting time-sensitive research investigating how BU predicts self- selection into drinking contexts, and how BU subsequently moderates the impact of those contexts. This K01 proposal, titled “Informing treatment adaptation using fine-grained context data in adolescent alcohol use” proposes to collect fine-grained data that could inform context-sensitive interventions, by informing when, where, and with whom to intervene, along with adaptation to sex- or context-specific situations. Equal numbers of male and female adolescents (N = 120, ages 15-17 years) who report at least one heavy drinking episode in the past two weeks, will be recruited for a 17-day ecological momentary assessment (EMA) survey preceded by a single laboratory session. The laboratory session will include self-report and behavioral assessments of BU as well as environmental factors. The EMA will include random user prompts as well as self-initiated reports assessing alcohol use, social, locational, and situational context characteristics, along with assessments of BU prior to, and after, alcohol use. The project has three specific research aims: 1) Examine whether context mediates the effect of BU on adolescent drinking. 2) Examine whether BU moderates the role of context in predicting adolescent drinking. 3) Examine how drinking impacts impulsivity, and how this impact predicts alcohol consequences. By informing context-sensitive interventions based on findings, we will capitalize on technology that allows for context-appropriate prompts (“Just-in-time” interventions). The associated training plan will provide the candidate with the ability to independently conduct EMA surveys among adolescents and aid in securing future funding, becoming a substantive expert on event-level context characteristics and individual traits using fine-grained assessment tools, and informing treatment adaptations for individual-differences-based interventions. Thus, the project is aligned at multiple levels with NIAAA’s underage drinking research initiative into investigating factors that drive harmful adolescent alcohol use.

项目概要在美国，未成年人饮酒是一个严重的健康问题，其病因是多方面的，而且范围广泛。影响范围广泛，包括危险情况（机动车事故、危险性行为和暴力）和酒精酒精使用障碍（青少年酒精使用障碍发病率最高）。个体特征与青少年饮酒行为的发展有关。环境水平、社会、地点和情境特征影响青少年的行为模式在个人层面上，未成年人饮酒最有力的个人预测因素之一是行为。控制不足（BU；例如冲动、寻求感觉）成功针对 BU 差异的干预措施。然而，研究表明，未成年饮酒者可以延迟饮酒并减少饮酒量。背景特征和 BU 的差异会有意义地改变饮酒行为。有机会调查背景效应如何因性别而异，并由 BU 调节以产生重事件层面的偶发性饮酒；通过进行时间敏感的研究来调查 BU 如何预测自我选择饮酒环境，以及 BU 随后如何调节这些环境的影响。提案的标题是“利用青少年酒精使用中的细粒度背景数据来告知治疗适应” 建议收集细粒度的数据，通过告知何时、在哪里、与谁进行干预，以及适应特定性别或具体情况的情况。报告至少一次酗酒事件的男性和女性青少年（N = 120，年龄 15-17 岁）过去两周，将招募参加为期 17 天的生态瞬时评估 (EMA) 调查实验室会议将包括自我报告和行为评估。 BU 以及环境因素将包括随机的用户提示以及自发的提示。评估酒精使用情况、社会、地点和情境特征的报告，以及该项目有三个具体研究目标：1) 检查。 2）检验BU是否调节作用预测青少年饮酒的背景 3) 检查饮酒如何影响冲动，以及这种影响如何。通过根据调查结果告知情境相关的干预措施，我们将预测酒精后果。利用能够提供适合上下文的提示的技术（“及时”干预）。相关的培训计划将为候选人提供独立进行 EMA 调查的能力青少年和援助以确保未来的资金，成为活动层面背景的实质性专家使用细粒度的评估工具来了解特征和个体特征，并为治疗适应提供信息因此，该项目在多个层面上与 NIAAA 保持一致。未成年人饮酒研究倡议旨在调查导致青少年有害饮酒的因素。