Interdisciplinary Program in Microbe-Host Biology

微生物-宿主生物学跨学科项目

• 批准号: 8742914
• 负责人: JOHN S GUNN
• 金额: $ 14.79万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-15 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8742914
• 关键词: Biology; Microbe; programs

DESCRIPTION (provided by applicant): Today's reality includes emergence and spread of multi-drug resistant organisms and new infectious agents, a growing concern for worldwide pandemics, the use of infectious agents in offensive bio-warfare, and an enlarging list of opportunistic infections. These challenges to human health necessitate comprehensive interdisciplinary training programs for the next generation of scientists in studies of the microbe host interface. The training faculty are from three colleges and several different departments. The hub for the program will be the Ohio State University Center for Microbial Interface Biology (CMIB), which is focused on Host-Pathogen Research. One of the PIs (MPI mechanism) is a physician scientist who serves as Director of the CMIB and Chair of a new Department in the Medical School, Microbial Infection and Immunity (MI&I), and the other PI is a PhD scientist and CMIB Vice-Director/MI&I Vice-Chair, both with strong research programs and careers focused on education. Thus the PIs represent an outstanding, established collaborative team to oversee this broad innovative program which emphasizes: 1) a highly interactive scientific community, 2) a multidisciplinary approach to science, 3) exposure of trainees to the biomedical research community of a large academic health sciences center, 4) integration of the clinical and basic sciences, 5) exposure to experienced and talented scientist educators and mentors, and 6) several added advantages to Fellows, including a local and international externship program. The major thematic areas are 1) Microbial response to infection; 2) Host response to infection (immunity, respiratory biology); 3) Biofilms; and 4) Drug discovery. The program describes a Selection and Oversight Committee, an outstanding, engaged External Advisory Committee and the necessary administrative structure to execute the program. Emphasis is placed on the recruitment of diversity trainees and on formal instruction for the responsible conduct of research. We request 3 pre-doctoral, 2 post-doctoral and 1 short-term clinical scholar slots/year. We believe that the curriculum, faculty, resources, and institutional support make this program attractive to outstanding students who will receive a unique multidisciplinary training experience focused on the microbe-host interface and prepare them for a career in the breadth of the biomedical workforce.

描述（由申请人提供）：当今的现实包括抗多药物的生物和新的感染剂的出现和传播，对全球大流行者的越来越关注，在进攻性生物 - 战争中使用传染性药物以及机会性感染的列表。对人类健康的这些挑战需要在微生物研究中为下一代科学家提供全面的跨学科培训计划 主机接口。培训学院来自三所大学和几个不同的系。该计划的枢纽将是俄亥俄州立大学微生物界面生物学中心（CMIB），该中心专注于宿主病原体研究。 PIS（MPI机制）之一是医师科学家，他是CMIB的主任兼医学院新部门主席，微生物感染和免疫（MI＆I）（MI＆I），另一个PI是博士学位科学家和CMIB副业副主席/MI/MI＆I和I MI＆I副主席，包括强有力的研究计划和专注于研究计划和医疗服务。因此，PI代表了一个杰出的，建立的合作团队，以监督这个广泛的创新计划，该计划强调：1）一个高度互动的科学界，2）一种多学科科学方法，3）受训者接触大型学术健康科学中心的生物医学研究社区，4）临床和基础科学的融合，5）5）教育家的融合，5）5）5）教育者和教育者6）研究员，包括当地和国际实习计划。主要主题区域是1）微生物对感染的反应； 2）宿主对感染的反应（免疫，呼吸生物学）； 3）生物膜； 4）毒品发现。该计划描述了一个选择和监督委员会，一个杰出的，参与的外部咨询委员会以及执行该计划的必要行政结构。重点放在招募多样性学员和负责任的研究的正式指导上。我们要求3个博士后，2个博士后和1个短期临床学者老虎机/年。我们认为，课程，教师，资源和机构支持使该计划对杰出学生有吸引力，他们将获得以微生物 - 主持人界面为重点的独特多学科培训经验，并为它们做好了生物医学员工的职业做好准备。