Interdisciplinary Program in Microbe-Host Biology

微生物-宿主生物学跨学科项目

• 批准号: 9438806
• 负责人: JOHN S GUNN
• 金额: $ 0.07万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9438806
• 关键词: Biology; Microbe; programs

DESCRIPTION (provided by applicant): Today's reality includes emergence and spread of multi-drug resistant organisms and new infectious agents, a growing concern for worldwide pandemics, the use of infectious agents in offensive bio-warfare, and an enlarging list of opportunistic infections. These challenges to human health necessitate comprehensive interdisciplinary training programs for the next generation of scientists in studies of the microbe host interface. The training faculty are from three colleges and several different departments. The hub for the program will be the Ohio State University Center for Microbial Interface Biology (CMIB), which is focused on Host-Pathogen Research. One of the PIs (MPI mechanism) is a physician scientist who serves as Director of the CMIB and Chair of a new Department in the Medical School, Microbial Infection and Immunity (MI&I), and the other PI is a PhD scientist and CMIB Vice-Director/MI&I Vice-Chair, both with strong research programs and careers focused on education. Thus the PIs represent an outstanding, established collaborative team to oversee this broad innovative program which emphasizes: 1) a highly interactive scientific community, 2) a multidisciplinary approach to science, 3) exposure of trainees to the biomedical research community of a large academic health sciences center, 4) integration of the clinical and basic sciences, 5) exposure to experienced and talented scientist educators and mentors, and 6) several added advantages to Fellows, including a local and international externship program. The major thematic areas are 1) Microbial response to infection; 2) Host response to infection (immunity, respiratory biology); 3) Biofilms; and 4) Drug discovery. The program describes a Selection and Oversight Committee, an outstanding, engaged External Advisory Committee and the necessary administrative structure to execute the program. Emphasis is placed on the recruitment of diversity trainees and on formal instruction for the responsible conduct of research. We request 3 pre-doctoral, 2 post-doctoral and 1 short-term clinical scholar slots/year. We believe that the curriculum, faculty, resources, and institutional support make this program attractive to outstanding students who will receive a unique multidisciplinary training experience focused on the microbe-host interface and prepare them for a career in the breadth of the biomedical workforce.

描述（由申请人提供）：当今的现实包括多重耐药生物体和新传染原的出现和传播、对世界范围内流行病的日益关注、传染原在进攻性生物战中的使用以及越来越多的机会性感染。这些对人类健康的挑战需要为下一代微生物研究科学家提供全面的跨学科培训计划 主机接口。培训师资来自三个学院和几个不同的部门。该项目的中心将是俄亥俄州立大学微生物界面生物学中心（CMIB），该中心专注于宿主-病原体研究。其中一名 PI（MPI 机制）是一位医师科学家，担任 CMIB 主任和医学院微生物感染与免疫 (MI&I) 新系主任，另一位 PI 是一名博士科学家和 CMIB 副主任。董事/MI&I 副主席，拥有强大的研究项目和专注于教育的职业生涯。因此，PI 代表了一个杰出的、成熟的合作团队来监督这一广泛的创新计划，该计划强调：1）高度互动的科学界，2）多学科的科学方法，3）让学员接触到大型学术健康的生物医学研究界科学中心，4) 临床和基础科学的整合，5) 接触经验丰富、才华横溢的科学家教育者和导师，以及 6) 研究员的一些额外优势，包括本地和国际实习计划。主要主题领域是 1) 微生物对感染的反应； 2）宿主对感染的反应（免疫、呼吸生物学）； 3）生物膜； 4) 药物发现。该计划描述了一个遴选和监督委员会、一个杰出的、积极参与的外部咨询委员会以及执行该计划所需的行政结构。重点放在招募多元化受训人员以及负责任地进行研究的正式指导上。我们要求每年 3 个博士前、2 个博士后和 1 个短期临床学者名额。我们相信，课程、师资、资源和机构支持使该项目对优秀学生具有吸引力，他们将获得专注于微生物-宿主界面的独特多学科培训经验，并为他们在生物医学领域的职业生涯做好准备。