Genomics Facility Core

基因组学设施核心

• 批准号: 9081595
• 负责人: George S Watts
• 金额: $ 13.1万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9081595
• 关键词: Genomics; Facility; Core

The objective of the Genomics facility core (GFC) is to provide full service applications of cutting-edge genomics technology to members of the SWEHSC. By consolidating genomics resources from its supporting institutions (the SWEHSC, the Arizona Cancer Center, and the Bio5 Institute), the GFC can offer cost-effective genomic analyses and ready access to local expertise. In particular, the expertise of the Core's directors enables the GFC to provide genome-wide analysis of the epigenetic effects of environmental toxicants. In addition to full service microarray-based analyses of gene expression, epigenetics, and copy number, the GFC provides consultation for sample preparation, sample quality control, and real time RT-PCR services in support of investigator's studies. Perhaps most importantly, the GFC has established dedicated data analysis support for investigators through the biostatistics arm of the Integrated Health Sciences Facility Core. The research highlights below were taken from projects that represent the SWEHSC's themes in populations of the southwest. The projects have been chosen from recent examples to demonstrate the newly integrated data analysis support along with the epigenetic capabilities within the GFC.

基因组学设施核心（GFC）的目的是提供尖端的全面服务应用 基因组技术给SWEHSC成员。通过从其支持中巩固基因组资源 机构（SWEHSC，亚利桑那癌症中心和Bio5研究所），GFC可以提供具有成本效益的 基因组分析并准备获得本地专业知识。特别是核心董事的专业知识 使GFC能够对环境有毒物质的表观遗传作用进行全基因组分析。在 除了基于基因表达，表观遗传学和复制号的基于全服务微阵列的分析，GFC 提供样品准备，样本质量控制和实时RT-PCR服务的咨询以支持 研究者的研究。也许最重要的是，GFC建立了专用的数据分析支持 通过综合健康科学设施核心的生物统计学部门为研究人员提供。研究 下面的亮点是从代表Swehsc主题人群中的项目中获取的 西南。这些项目是从最近的示例中选择的，以证明新集成的数据 分析支持以及GFC内的表观遗传能力。