Biomedical Statistics Core

生物医学统计核心

• 批准号: 10574517
• 负责人: Ross D Crosby
• 金额: $ 36.49万
• 依托单位: SANFORD RESEARCH NORTH
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10574517
• 关键词: Area; Biometry; Centers of Research Excellence; Clinical Research; Collaborations; Consultations; Data; Data Analytics; Data Collection; Data Storage and Retrieval; Development; Eating Behavior; Eating Disorders; Ecological momentary assessment; Education; Educational Activities; Educational workshop; Ethics; Faculty; FarGo; Grant; Individual; Infrastructure; Institution; Interview; Laboratories; Machine Learning; Maintenance; Mentors; Methodology; Methods; Modality; Monitor; North Dakota; Patient Self-Report; Pharmacologic Substance; Phase; Preparation; Process; Protocols documentation; Psychology; Psychophysiology; Publications; Questionnaires; Research; Research Design; Research Personnel; Sample Size; Science; Services; Statistical Data Interpretation; Structure; Testing; Training; Translational Research; Universities; Work; Writing; biobehavior; cognitive testing; data management; experience; handheld mobile device; human subject; innovation; interest; medical schools; multimodal data; neuroimaging; power analysis; research and development; skills; statistics; tool; training opportunity; training project

Biomedical Statistics Core Center for Bio-behavioral Mechanisms of Eating Behavior SUMMARY/ABSTRACT We propose to establish a Center of Biomedical Research Excellence (COBRE) at the Sanford Center for Bio- behavioral Research (SCBR; Fargo, ND) in collaboration with the North Dakota State University (NDSU) Departments of Psychology and Pharmaceutical Sciences and the University of North Dakota School of Medicine (UNDSOM). This center will focus on conducting cutting-edge, innovative research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. The purpose of the Biomedical Statistics Core (BSC) is to create a methodological and statistical infrastructure supporting clinical and translational research and education focused on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. This core will allow efficient access to methodological and biostatistical support by providing consultation, methodological and statistical support services, educational activities, and methodological and statistical mentoring and training opportunities. Objectives 1. To develop and implement a BSC at Sanford Center for Bio-behavioral Research that will provide and maintain high quality methodological and statistical consultation and support services for clinical and translational research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. 2. To provide methodological and statistical educational opportunities for COBRE Project Directors and faculty in the form of seminars, colloquia, and workshops. These educational opportunities will focus on methods for identifying and evaluating mechanistic processes. 3. To provide mentoring and hands-on training opportunities for COBRE Project Directors and faculty interested in gaining analytic experience and further developing their statistical and methodological skills. Methods The BSC will work with the COBRE Project Directors during the pre-grant, grant, and post-grant periods, assisting in study design, sample size calculation, power analysis, data collection methods, data storage and management, ongoing study monitoring, statistical analysis, interpretations of results, and assistance in preparation of presentations and publications. The BSC will work with the Administrative Core and Human Subjects Core to provide relevant training opportunities in the areas of the ethical conduct of research, research design (e.g., sample size calculation and power analysis), mechanistic data analytic approaches, grant writing, and professional development. In addition to these training opportunities, the BSC will also provide more intensive training in the form of ongoing mentoring or regular hands-on training for Project Directors who are interested in expanding their analytic capabilities.

生物医学统计核心 饮食行为生物行为机制中心 摘要/摘要 我们建议在桑福德生物医学中心建立一个生物医学研究卓越中心（COBRE） 与北达科他州立大学 (NDSU) 合作的行为研究（SCBR；北达科他州法戈） 心理学系和药学系以及北达科他大学医学院 医学（联合国索马里援助团）。该中心将重点开展前沿、创新研究 与饮食失调和饮食行为的发生和维持相关的机制。目的 生物医学统计核心（BSC）旨在创建一个方法和统计基础设施，支持 临床和转化研究和教育侧重于与发病和相关的机制 维持饮食失调和饮食行为。该核心将允许有效地访问方法论 通过提供咨询、方法和统计支持服务来提供生物统计支持， 教育活动以及方法和统计指导和培训机会。 目标 1. 在桑福德生物行为研究中心制定并实施平衡计分卡，该平衡计分卡将提供和 维持高质量的方法学和统计咨询以及临床和支持服务 与饮食失调的发生和维持相关的机制的转化研究 饮食行为。 2. 为 COBRE 项目总监和 教师以研讨会、座谈会和讲习班的形式进行。这些教育机会将集中于 识别和评估机械过程的方法。 3. 为COBRE项目总监和教员提供指导和实践培训机会 有兴趣获得分析经验并进一步发展他们的统计和方法技能。 方法 BSC 将在拨款前、拨款和拨款后期间与 COBRE 项目总监合作， 协助研究设计、样本量计算、功效分析、数据收集方法、数据存储和 管理、持续研究监测、统计分析、结果解释以及协助 准备演示文稿和出版物。 BSC 将与行政核心和人力资源部门合作 科目核心提供研究道德行为领域的相关培训机会， 研究设计（例如样本量计算和功效分析）、机械数据分析方法、 拨款写作和专业发展。除了这些培训机会外，平衡计分卡还将 以持续指导或定期项目实践培训的形式提供更强化的培训 有兴趣扩展分析能力的董事。