Evaluating New Nicotine Standards for Cigarettes

评估卷烟新尼古丁标准

基本信息

批准号：
10578938
负责人：
ERIC Christian DONNY
金额：
$ 32.21万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-15 至 2024-02-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10578938
关键词：
Adult Age Area Attitude Behavior Behavioral Belief Biological Markers Cigarette Communities Complex Country Data Decision Making Dependence Enrollment Ensure Ethnic group Exposure to Funding Future Generations Goals Government Health Health Benefit Health Promotion Health behavior Heavy Drinking Indigenous Individual Interview Laws Leadership Learning Measures Mental Depression Mental Health Methods New Zealand Nicotine Pacific Islander Participant Perception Personal Satisfaction Persons Policies Population Public Health Qualitative Research Randomized Clinical Trials Recording of previous events Regulation Reporting Research Research Personnel Risk Risk Factors Sales Sampling Services Smoke Smoker Smoking Subgroup Surveys Time Tobacco Tobacco Dependence Tobacco Industry Tobacco smoke Tobacco use United States Food and Drug Administration Universities Woman Work Youth base biobank cigarette smoking cohort design environmental tobacco smoke exposure health inequalities low nicotine content cigarette marijuana use recruit response self-reported anxiety smoking cessation smoking during pregnancy smoking prevalence socioeconomics tobacco products tobacco user young adult

项目摘要

PROJECT SUMMARY On December 9, 2021, the New Zealand Government launched the Smokefree Aotearoa 2025 Action Plan, outlining a strategy to reduce smoking prevalence to less than 5% for all populations in New Zealand by 2025. The plan includes a commitment to only having low-level nicotine smoked tobacco products for sale. A low nicotine product standard has also been proposed as a cornerstone of the United States Food and Drug Administration’s Comprehensive Plan for Tobacco and Nicotine Regulation. Previous research has demonstrated that when tobacco users switch to very low nicotine content cigarettes there is a reduction in cigarettes per day, dependence and biomarkers of smoke exposure, plus an increase in quit attempts and smoking cessation; and relatively few unintended consequences. However, to date, no country has implemented a low nicotine product standard; therefore, the real world impact of regulation has not been evaluated. We propose to conduct an exploratory sequential mixed methods study in New Zealand adults who smoke tobacco cigarettes to assess product perceptions, concerns for individual health and well-being, need for support services, and behavioral intentions in response to a pending mandated reduction of nicotine in all smoked tobacco products. The survey will also include items from a wide range of domains including tobacco use behaviors; tobacco dependence; attitudes, beliefs, and norms; other health behaviors; significant health conditions and associated risk factors; mental health indicators; and smoking cessation history. Biosamples will be banked in a biorepository located at the University of Auckland for future analysis of changes in objective measures of exposure to tobacco smoke. The proposed research focuses on populations with high smoking prevalence (oversampling important ethnic groups: Maori, Pacific Islanders), including: 1) Individuals with self-reported anxiety, depression and other mental health concerns; 2) Young adult women (age 18-24 years) living in socioeconomically deprived areas of New Zealand who are at a much greater risk of smoking during pregnancy; and 3) Individuals who report heavy alcohol and/or cannabis use.

项目概要 2021年12月9日，新西兰政府启动了《无烟新西兰2025行动计划》，概述了到 2025 年将新西兰所有人口的吸烟率降低到 5% 以下的战略。该计划包括承诺只销售低尼古丁含量的烟草产品。尼古丁产品标准也被提议作为美国食品和药品管理局的基石政府的烟草和尼古丁监管综合计划之前的研究已经完成。研究表明，当烟草使用者改用尼古丁含量极低的香烟时，尼古丁含量会减少每天吸烟的数量、依赖性和烟雾暴露的生物标志物，加上戒烟尝试的增加和戒烟；以及相对较少的意外后果。然而，迄今为止，还没有国家做到这一点。实施了低尼古丁产品标准；因此，监管对现实世界的影响尚未得到体现。我们建议对新西兰成年人进行一项探索性序贯混合方法研究。吸烟以评估产品认知、对个人健康和福祉的关注、需求支持服务和行为意图，以应对所有未决的强制减少尼古丁的情况该调查还将包括烟草等广泛领域的项目。使用行为；态度、信仰和规范；状况和相关危险因素；心理健康指标；以及戒烟史。将储存在位于奥克兰大学的生物储存库中，以供未来分析变化拟议的研究重点是烟草烟雾暴露的客观测量。吸烟率（对重要种族群体进行过采样：毛利人、太平洋岛民），包括：1) 个人 2）自我报告有焦虑、抑郁和其他心理健康问题的年轻成年女性（18-24岁）；年）生活在新西兰社会贫困地区的人吸烟的风险要大得多怀孕期间；和 3) 报告酗酒和/或吸食大麻的人。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Randomized Trial of Reduced-Nicotine Standards for Cigarettes.

香烟尼古丁含量降低标准的随机试验。

DOI：
发表时间：
2015-10
期刊：
影响因子：
0
作者：
Donny, Eric C;Denlinger, Rachel L;Tidey, Jennifer W;Koopmeiners, Joseph S;Benowitz, Neal L;Vandrey, Ryan G;al'Absi, Mustafa;Carmella, Steven G;Cinciripini, Paul M;Dermody, Sarah S;Drobes, David J;Hecht, Stephen S;Jensen, Joni;Lane, Tonya;Le
通讯作者：
Le

Low-dose nicotine self-administration is reduced in adult male rats naïve to high doses of nicotine: implications for nicotine product standards.

初次接触高剂量尼古丁的成年雄性大鼠的低剂量尼古丁自我给药减少：对尼古丁产品标准的影响。

DOI：
发表时间：
2014-10
期刊：
影响因子：
2.3
作者：
Smith, Tracy T;Schassburger, Rachel L;Buffalari, Deanne M;Sved, Alan F;Donny, Eric C
通讯作者：
Donny, Eric C

The predicted impact of reducing the nicotine content in cigarettes on alcohol use.

减少香烟中尼古丁含量对饮酒的预计影响。

DOI：
发表时间：
2014-08
期刊：
影响因子：
0
作者：
Dermody, Sarah S;Donny, Eric C
通讯作者：
Donny, Eric C

Nicotine and Anatabine Exposure from Very Low Nicotine Content Cigarettes.

尼古丁含量极低的香烟中尼古丁和新阿他滨的暴露。

DOI：
发表时间：
2016-04
期刊：
影响因子：
0
作者：
Denlinger, Rachel L;Smith, Tracy T;Murphy, Sharon E;Koopmeiners, Joseph S;Benowitz, Neal L;Hatsukami, Dorothy K;Pacek, Lauren R;Colino, Cirielle;Cwalina, Samantha N;Donny, Eric C
通讯作者：
Donny, Eric C

Dose-response effects of spectrum research cigarettes.

光谱研究香烟的剂量反应效应。

DOI：
发表时间：
2013-06
期刊：
影响因子：
0
作者：
Hatsukami, Dorothy K;Heishman, Stephen J;Vogel, Rachel Isaksson;Denlinger, Rachel L;Roper;Mackowick, Kristen M;Jensen, Joni;Murphy, Sharon E;Thomas, Brian F;Donny, Eric
通讯作者：
Donny, Eric