Southern Consortium Node of the Clinical Trials Network

临床试验网络南方联盟节点

• 批准号: 8921318
• 负责人: KATHLEEN T. BRADY
• 金额: $ 42.73万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8921318
• 关键词: Area; Award; Clinic; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Design; Clinical Trials Network; Clinical and Translational Science Awards; Collaborations; Communities; Comorbidity; Data; Development; Evidence based practice; Funding; Geographic Distribution; Goals; HIV; Health; Health Personnel; Human Resources; Individual; Informatics; Institution; Medical; Medical Research; Mission; Mississippi; Modeling; Multi-Institutional Clinical Trial; National Institute of Drug Abuse; North Carolina; Participant; Persons; Primary Health Care; Principal Investigator; Research; Research Activity; Research Personnel; Resources; Science; Site; South Carolina; Structure; System; Tennessee; Training; Translational Research; Translations; U-Series Cooperative Agreements; United States National Institutes of Health; Universities; Work; addiction; community based participatory research; comparative efficacy; design; dissemination research; effective therapy; efficacy research; experience; flexibility; health disparity; implementation research; improved; medical specialties; next generation; patient population; research to practice; treatment program

DESCRIPTION (provided by applicant): Since 2000, the Southern Consortium Node (SCN) has worked closely with community partners and colleagues nationwide in research and dissemination activities designed to improve the treatment of addictions through research and implementation of evidence-based practice. In this renewal application, the SCN proposes to expand to include a broader region of the southeast through partnership with Duke University, a national leader in medical research. Duke University is an ideal partner because of their complementary scientific expertise, strong primary care and HIV research activities, geographic proximity and prior experience with CTN activities. The partnership will extend the SCN's regional and geographic distribution to span a large portion of the Southeastern US and bring close connections with well-established primary care and HIV clinical research networks to broaden the types of clinical settings and patient populations available for CTN trials. The SCN will establish a robust collaboration with the CTSA initiative through a number of individuals who will serve as investigators on both the CTN and CTSA, including Dr. Brady who is the PI of the MUSC CTSA. The primary specific aims for the next five years are: to extend the geographic reach of the SCN to include CTPs and academic partners in South Carolina, North Carolina, Georgia, Tennessee and Mississippi. To develop research sites in primary care and medical specialty clinics that will expand the diversity of and number of participants available to participate in CTN trials. To increase the use of CTN as a training platform and a research platform for non-CTN research. To develop a robust collaboration between the CTN and both local and national CTSAs for the purpose of bidirectional sharing of "best-practices", informatics and trial design strategies across networks. To expand the scientific expertise available to the CTN through partnership of investigators at MUSC and Duke University.

描述（由申请人提供）：自2000年以来，南部财团节点（SCN）与全国社区伙伴和同事紧密合作，从事研究和传播活动，旨在通过研究和实施基于循证的实践来改善成瘾的治疗。在此续签应用程序中，SCN建议通过与医学研究的国家领导人杜克大学合作，将其扩展为包括东南部更广泛的地区。杜克大学之所以成为理想的合作伙伴，是因为他们拥有互补的科学专业知识，强大的初级保健和艾滋病毒研究活动，地理位置邻近性以及CTN活动的先前经验。该合作伙伴关系将扩大SCN的区域和地理分布，以跨越美国东南部的很大一部分，并与成熟的初级保健和HIV临床研究网络建立了密切的联系，以扩大可用于CTN试验的临床环境和患者种群的类型。 SCN将通过许多个人将在CTN和CTSA担任调查人员，包括MUSC CTSA的PI，包括Brady博士，与CTSA计划建立了强大的合作。 未来五年的主要特定目的是：将SCN的地理范围扩展到包括南卡罗来纳州，北卡罗来纳州，乔治亚州，田纳西州和密西西比州的CTP和学术合作伙伴。 在初级保健和医学专业诊所开发研究地点，以扩大参与CTN试验的参与者的多样性和数量。增加使用CTN作为培训平台和非CTN研究的研究平台。为了建立CTN与本地和国家CTSA之间的强大合作，以便双向共享“最佳实践”，信息学和试验设计策略。通过MUSC和杜克大学的调查人员合作，扩大了CTN可用的科学专业知识。