Southern Consortium Node of the Clinical Trials Network

临床试验网络南方联盟节点

• 批准号: 9765878
• 负责人: KATHLEEN T. BRADY
• 金额: $ 17.81万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9765878
• 关键词: Acute; Address; Adolescent; Adoption; Adult; Alcohol or Other Drugs use; Alcohols; Area; Bioinformatics; Caring; Chronic; Chronic Care; Chronic Disease; Cigarette Smoker; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical and Translational Science Awards; Communication; Communities; Conduct Clinical Trials; Continuity of Patient Care; Contracts; Cost Analysis; Data; Disease Management; Electronic Health Record; Evidence based practice; Federally Qualified Health Center; Goals; Health Care Costs; Health Personnel; Health Technology; Healthcare; Healthcare Systems; Hospitals; Incentives; Individual; Informatics; Information Technology; Institution; Intervention; Investigation; Legal; Mainstreaming; Medical; Methods; Multi-Institutional Clinical Trial; National Institute of Drug Abuse; Nicotine; Oral health; Participant; Patients; Peer Review; Population; Positioning Attribute; Prevention; Primary Health Care; Publications; Relapse; Research; Research Personnel; Risk; Science; Services; South Carolina; Substance Use Disorder; System; Technology; Telemedicine; Testing; Translational Research; Treatment outcome; U-Series Cooperative Agreements; United States; Universities; Work; addiction; aged; base; brief intervention; chronic care model; clinical practice; comparative effectiveness; cost effective; design; effective intervention; effectiveness trial; follow-up; health care cost/financing; health care delivery; health care settings; illicit drug use; improved; innovation; mHealth; medical specialties; member; multidisciplinary; new technology; novel strategies; patient registry; practice setting; practice-based research network; pragmatic trial; prescription opioid; primary care setting; programs; recruit; screening; screening, brief intervention, referral, and treatment; success; symposium; treatment services; trial design; user-friendly

Abstract The NIDA Clinical Trials Network (CTN) offers the ideal platform to evaluate innovative methods, thereby potentiating technology-driven comparative effectiveness trials in a variety of treatment settings. This renewal application builds upon years of success in the Southern Consortium Node (SCN) of the CTN. Since our inception in 2000, we have built and sustained an outstanding team of inter-professional experts in addictions treatment and research, conducted an array of well-managed clinical trials, and disseminated findings through traditional communication channels, such as professional conferences and peer-reviewed publications. We recognize that in order to have meaningful population impact, treatments must be well integrated into healthcare practices and treatment delivery systems. With this renewal, we capitalize on recent successes in conducting clinical trials in a wide range of healthcare settings that make use of new technologically based methods to screen and treat individuals with substance use disorders (SUDs). Acute care management of SUDs within medical settings (i.e. SBIRT strategies to screen, briefly intervene, and refer to treatment) insufficiently addresses the chronic care needs of SUD patients that are so often marked by relapse. We propose a more comprehensive approach, including chronic care management, based on a broader translational view, using novel, technology-driven strategies to improve screening, increase delivery and efficacy of brief interventions, optimize referrals to specialty care, and develop systems to address the chronic relapsing course of many SUDs. We emphasize the exploration of approaches that are not only effective, but also cost-effective, so as to promote adoption into clinical practice settings. We bring to the network a research team with expertise in the integration of substance use screening, intervention delivery, and referral within primary care and other health care settings. Building on existing strengths in addictions research at MUSC, we have assembled a multi-disciplinary team with expertise in addiction treatment, primary care, bioinformatics, mobile health, health care cost analysis and clinical research to focus on the investigation of effective screening and treatment interventions for SUDs in a variety of settings. We are ideally suited to continue as active members of the CTN consortium in exploring efficient and effective ways to integrate addictions treatment into mainstream medical care. In doing so, we will meet new challenges and take advantage of growing opportunities within the changing healthcare system.

抽象的 NIDA 临床试验网络 (CTN) 提供了评估创新方法的理想平台，从而 加强各种治疗环境中技术驱动的比较有效性试验。此次续订 该应用程序建立在 CTN 南方联盟节点 (SCN) 多年成功的基础之上。自从我们的 自2000年成立以来，我们建立并维持了一支由成瘾领域的跨专业专家组成的优秀团队 治疗和研究，进行了一系列管理良好的临床试验，并通过 传统的沟通渠道，例如专业会议和同行评审出版物。我们 认识到为了对人群产生有意义的影响，治疗必须很好地融入到 医疗保健实践和治疗提供系统。通过这次更新，我们利用了最近在 利用基于新技术的技术在广泛的医疗保健环境中进行临床试验 筛查和治疗患有物质使用障碍 (SUD) 的个体的方法。急症护理管理 医疗环境中的 SUD（即筛查、短暂干预和转诊治疗的 SBIRT 策略） 不足以满足经常复发的 SUD 患者的长期护理需求。我们 提出更全面的方法，包括基于更广泛的长期护理管理 转化观点，使用新颖的、技术驱动的策略来改进筛选、增加交付和 简短干预措施的有效性，优化专业护理转诊，并开发解决慢性病的系统 许多 SUD 的复发过程。我们强调探索不仅有效，而且 也具有成本效益，从而促进临床实践环境的采用。我们为网络带来 研究团队在物质使用筛查、干预实施和转诊整合方面拥有专业知识 在初级保健和其他医疗保健机构中。建立在成瘾研究的现有优势的基础上 MUSC，我们组建了一支多学科团队，在成瘾治疗、初级保健、 生物信息学、移动健康、医疗保健成本分析和临床研究重点调查 在各种环境下对 SUD 进行有效的筛查和治疗干预。我们非常适合 继续作为CTN联盟的积极成员，探索高效、有效的整合方式 成瘾治疗纳入主流医疗保健。在此过程中，我们将迎接新的挑战， 利用不断变化的医疗保健系统中不断增长的机会。