Southern Consortium Node of the Clinical Trials Network

临床试验网络南方联盟节点

• 批准号: 9765878
• 负责人: KATHLEEN T. BRADY
• 金额: $ 17.81万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-01 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9765878
• 关键词: Acute; Address; Adolescent; Adoption; Adult; Alcohol or Other Drugs use; Alcohols; Area; Bioinformatics; Caring; Chronic; Chronic Care; Chronic Disease; Cigarette Smoker; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical and Translational Science Awards; Communication; Communities; Conduct Clinical Trials; Continuity of Patient Care; Contracts; Cost Analysis; Data; Disease Management; Electronic Health Record; Evidence based practice; Federally Qualified Health Center; Goals; Health Care Costs; Health Personnel; Health Technology; Healthcare; Healthcare Systems; Hospitals; Incentives; Individual; Informatics; Information Technology; Institution; Intervention; Investigation; Legal; Mainstreaming; Medical; Methods; Multi-Institutional Clinical Trial; National Institute of Drug Abuse; Nicotine; Oral health; Participant; Patients; Peer Review; Population; Positioning Attribute; Prevention; Primary Health Care; Publications; Relapse; Research; Research Personnel; Risk; Science; Services; South Carolina; Substance Use Disorder; System; Technology; Telemedicine; Testing; Translational Research; Treatment outcome; U-Series Cooperative Agreements; United States; Universities; Work; addiction; aged; base; brief intervention; chronic care model; clinical practice; comparative effectiveness; cost effective; design; effective intervention; effectiveness trial; follow-up; health care cost/financing; health care delivery; health care settings; illicit drug use; improved; innovation; mHealth; medical specialties; member; multidisciplinary; new technology; novel strategies; patient registry; practice setting; practice-based research network; pragmatic trial; prescription opioid; primary care setting; programs; recruit; screening; screening, brief intervention, referral, and treatment; success; symposium; treatment services; trial design; user-friendly

Abstract The NIDA Clinical Trials Network (CTN) offers the ideal platform to evaluate innovative methods, thereby potentiating technology-driven comparative effectiveness trials in a variety of treatment settings. This renewal application builds upon years of success in the Southern Consortium Node (SCN) of the CTN. Since our inception in 2000, we have built and sustained an outstanding team of inter-professional experts in addictions treatment and research, conducted an array of well-managed clinical trials, and disseminated findings through traditional communication channels, such as professional conferences and peer-reviewed publications. We recognize that in order to have meaningful population impact, treatments must be well integrated into healthcare practices and treatment delivery systems. With this renewal, we capitalize on recent successes in conducting clinical trials in a wide range of healthcare settings that make use of new technologically based methods to screen and treat individuals with substance use disorders (SUDs). Acute care management of SUDs within medical settings (i.e. SBIRT strategies to screen, briefly intervene, and refer to treatment) insufficiently addresses the chronic care needs of SUD patients that are so often marked by relapse. We propose a more comprehensive approach, including chronic care management, based on a broader translational view, using novel, technology-driven strategies to improve screening, increase delivery and efficacy of brief interventions, optimize referrals to specialty care, and develop systems to address the chronic relapsing course of many SUDs. We emphasize the exploration of approaches that are not only effective, but also cost-effective, so as to promote adoption into clinical practice settings. We bring to the network a research team with expertise in the integration of substance use screening, intervention delivery, and referral within primary care and other health care settings. Building on existing strengths in addictions research at MUSC, we have assembled a multi-disciplinary team with expertise in addiction treatment, primary care, bioinformatics, mobile health, health care cost analysis and clinical research to focus on the investigation of effective screening and treatment interventions for SUDs in a variety of settings. We are ideally suited to continue as active members of the CTN consortium in exploring efficient and effective ways to integrate addictions treatment into mainstream medical care. In doing so, we will meet new challenges and take advantage of growing opportunities within the changing healthcare system.

抽象的 NIDA临床试验网络（CTN）提供了评估创新方法的理想平台 在各种治疗环境中增强技术驱动的比较有效性试验。这个更新 应用在CTN的南部联盟节点（SCN）的成功基础上。自从我们 2000年成立于2000年，我们建立并维持了一支杰出的成瘾专家团队 治疗和研究，进行了一系列管理良好的临床试验，并通过 传统的沟通渠道，例如专业会议和同行评审的出版物。我们 认识到，为了产生有意义的人口影响，必须将治疗方法很好地融入 医疗保健实践和治疗输送系统。通过这种续约，我们利用了最近的成功 在广泛的医疗机构中进行临床试验，以利用新技术 筛查和治疗患有药物使用障碍（SUD）的人的方法。急性护理管理 在医疗环境中的泡沫（即筛查，简短干预并参考治疗的策略） 不足以满足经常以复发为特征的SUD患者的慢性护理需求。我们 提出一种更全面的方法，包括慢性护理管理，基于更广泛的 转化视图，采用新颖的技术驱动策略来改善筛选，增加交付和 简短干预措施的功效，优化对专业护理的推荐并开发系统以解决慢性 许多肥皂水的复发过程。我们强调对不仅有效的方法的探索，而且还 也具有成本效益，以促进对临床实践环境的收养。我们将网络带到网络 具有专业知识的研究团队，用于整合物质使用筛查，干预交付和推荐 在初级保健和其他医疗保健环境中。基于成瘾研究中现有优势 MUSC，我们已经组建了一个具有成瘾治疗，初级保健，初级专业知识的多学科团队 生物信息学，移动健康，医疗保健成本分析和临床研究，以关注调查 在各种环境中对SUD的有效筛查和治疗干预措施。我们非常适合 继续担任CTN联盟的活跃成员，以探索有效的整合方法 成瘾治疗主流医疗保健。这样，我们将面临新的挑战并接受 不断变化的医疗保健系统中机会增长的优势。