Clinical and Translational Science Institute

临床与转化科学研究所

• 批准号: 8737324
• 负责人: Jennifer Rubin Grandis
• 金额: $ 1937.01万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8737324
• 关键词: Academic Medical Centers; Acceleration; Accountability; Advocacy; Area; Basic Science; Biological Models; Biomedical Engineering; Businesses; California; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communication; Communities; Community Practice; Consultations; Contracts; Data; Data Set; Development; Diagnostic tests; Distance Learning; Doctor of Medicine; Doctor of Philosophy; Engineering; Environment; Epidemiology; Faculty; Fostering; Funding; Goals; Health; Health Policy; Healthcare; Home environment; Hour; Improve Access; Industry; Informatics; Institutes; Institution; Institutional Review Boards; Interdisciplinary Study; Internships; Intervention; Knowledge; Leadership; Medical Records; Metric; Mission; Modeling; Multicenter Studies; Participant; Patients; Performance; Phase; Policies; Principal Investigator; Public Health; Regulation; Research; Research Infrastructure; Research Personnel; Research Training; Rewards; San Francisco; Schools; Series; Services; Site; Students; Training; Training Programs; Training and Infrastructure; Translational Research; Trust; Underrepresented Minority; Universities; Work; base; catalyst; clinical application; cost effectiveness; design; evidence base; improved; innovation; meetings; multidisciplinary; programs; randomized trial; skills; success; tool; translational medicine; virtual

DESCRIPTION (provided by applicant): We established the UCSF Clinical and Translational Science Institute (CTSI) at the University of California, San Francisco (UCSF) in 2006 to accelerate the pace of research that improves the health of the public. The overall mission of CTSI has been to improve and transform clinical and translational research infrastructure and training at UCSF and our partner institutions. In the next funding period we aim to use the substantial knowledge, skills, and infrastructure that we have developed to further accelerate the pace of research at UCSF, to export our successes to other institutions, and to create initiatives aimed at improving the health of our own and other communities, through the following aims: SPECIFIC AIM 1: To enhance the highly successful activities of the UCSF CTSI, including the development of new initiatives in the areas of Training, Infrastructure/Services, and Advocacy/Culture Change: a) Training: to provide programs for students at all levels, across a spectrum of settings, and including all phases of the improvement of healthcare; b) Infrastructure/Services: to expand services and tools to clinical and translational investigators at UCSF, our partner institutions, and within the broader regional, national, and global communities; and, c) Advocacy/Culture Change: to nurture communication, encourage collaboration, foster innovation, and catalyze the successful conduct of clinical and translational research; to support a diverse faculty; to increase involvement of the community and the responsive of research to its needs; and change the academic culture to promote multidisciplinary, collaborative work. SPECIFIC AIM 2: To develop crosscutting initiatives using the knowledge, skills, and infrastructure developed by multiple CTSI programs in the first funding period to accelerate clinical and translational research and its impact on health, well beyond the institutions collaborating in the UCSF CTSI. New initiatives will: a) Bring together local public health and philanthropic groups to work with CTSI to improve the health of the San Francisco Bay Area community through a series of health improvement projects directed at high impact conditions; b) create a model system to accelerate the pace of clinical and translational research that includes streamlining regulation, developing participant recruitment services, providing research management, and bringing research services directly into community practices; and, c) improve the performance, transparency and accountability of research administration within and beyond CTSI by setting challenging goals and tracking performance metrics on public dashboards. These aims will be achieved by orchestration of activities occurring within and between our 10 programs, supported by a proven governance model, and with strong ties to institutional and community leadership. Our ultimate goal is to bring better health to more people more quickly.

描述（由申请人提供）：我们于2006年在加利福尼亚大学旧金山分校（UCSF）建立了UCSF临床和转化科学研究所（CTSI），以加快改善公众健康状况的研究步伐。 CTSI的总体使命是改善和改变UCSF及我们的合作伙伴机构的临床和转化研究基础设施和培训。在下一个资金期间，我们旨在利用我们开发的大量知识，技能和基础设施来进一步加速UCSF的研究步伐，将我们的成功导出到其他机构，并创建旨在通过以下目的来改善我们自己和其他社区健康的计划： 具体目的1：为了增强UCSF CTSI的非常成功的活动，包括在培训，基础设施/服务以及倡导/文化变化领域的新举措的制定： b）基础设施/服务：将服务和工具扩展到UCSF，我们的合作伙伴机构以及更广泛的地区，国家和全球社区的临床和翻译调查员； c）倡导/文化变化：培养沟通，鼓励协作，促进创新并促进临床和转化研究的成功进行；支持多元化的教师；增加社区的参与以及研究对其需求的反应；并改变学术文化，以促进多学科的协作工作。 具体目标2：使用由多个CTSI计划在第一个资金期间开发的知识，技能和基础设施制定横切计划，以加速临床和转化研究及其对健康的影响，远远超出了UCSF CTSI合作的机构。新举措将：a）通过一系列针对高影响力条件的健康改善项目，将当地的公共卫生和慈善团体聚集在一起与CTSI合作，以改善旧金山湾区社区的健康； b）创建一个模型系统，以加快临床和转化研究的速度，包括简化监管，开发参与者招聘服务，提供研究管理以及将研究服务直接带入社区实践；并且，c）通过设定挑战性目标并跟踪公共仪表板上的绩效指标，提高CTSI内外研究管理的绩效，透明度和问责制。 这些目标将通过在我们的10个计划内部和在我们的10个计划内部的活动进行编排，并得到了经过验证的治理模型的支持，并且与机构和社区领导力有着密切的联系。我们的最终目标是更快地为更多的人带来更好的健康。