Training Program in Cancer Prevention and Control for Priority Populations

重点人群癌症预防和控制培训项目

• 批准号: 10238055
• 负责人: Guy H Montgomery
• 金额: $ 25.09万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-21 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10238055
• 关键词: Cancer Control; Population; Training Programs; cancer prevention

PROJECT ABSTRACT More than 600,000 Americans will die of cancer in 2017. While cancer affects the entire US population, it has the distinct feature of striking disparities in incidence and mortality across several `priority' populations such as racial/ethnic minorities, the low-income, and the elderly, reflecting differences in risk factors and access to prevention and treatments. The National Cancer Institute highlighted the interplay of environment, biology and behavior as determinants of cancer outcomes in priority populations and the need for its integration in cancer prevention and control (CPC) efforts, signaling a greater need for multidisciplinary approaches to CPC research for priority populations. Such complex approaches require developing highly trained research scientists with a multidisciplinary `mindset': the enthusiasm and appreciation for working across disciplines to gain new perspectives on old problems and develop innovative solutions. And yet, the development pipeline for such investigators is inadequate to match the growing burden of cancer and cancer risk in priority populations. The overarching goal of the proposed CPC postdoctoral research training program is to launch the careers of a new generation of clinical and non-clinical researchers prepared to apply this multidisciplinary approach to CPC research targeting priority populations. The program's goals are to: 1) Provide a tailored curriculum integrating biological, medical, epidemiologic, behavioral, and community perspectives in CPC research in priority populations; 2) Promote interdisciplinary approaches to CPC research; and 3) Foster multidisciplinary research careers in CPC among trainees through mentored research. To successfully execute these aims, the program will recruit candidates who show promise as future multidisciplinary CPC investigators; provide outstanding mentorship; foster a multidisciplinary team science environment; and facilitate the attainment of academic career and life skills needed to pursue and sustain long term success as independent investigators. The program's strengths will lie in the diverse CPC research portfolio at Mount Sinai, its integration in the newly NCI-accredited Tisch Cancer Institute, the network of methodologically diverse and accomplished mentors, and Mount Sinai's long history of serving the socioeconomically, racially and ethnically diverse communities that comprise its catchment area. It is modeled after our highly successful prior R25T Behavioral CPC training program. The program will matriculate 2 candidates each year for the 2-year fellowship, training a total of 10 new investigators over 5 years. Each trainee will develop a highly tailored curriculum in consultation with their mentors and the Program Directors. The curricula will be rooted in the 11 core competencies needed to start a successful career in multidisciplinary CPC research targeting priority populations. Trainees will have a primary and secondary mentor(s), and their progress will be carefully monitored by a Mentorship Committee. The program will receive guidance from expert internal and external advisory boards, and its performance will be regularly monitored through select metrics to ensure continued improvement, growth, and sustainability.

项目摘要 2017 年将有超过 60 万美国人死于癌症。虽然癌症影响着整个美国人口，但它已经 几个“重点”人群的发病率和死亡率存在显着差异的显着特征，例如 种族/族裔少数群体、低收入群体和老年人，反映了风险因素和获取途径的差异 预防和治疗。美国国家癌症研究所强调了环境、生物学和 行为作为优先人群癌症结果的决定因素以及将其纳入癌症的必要性 预防和控制 (CPC) 工作，表明更需要采取多学科方法来预防和控制 (CPC) 针对优先人群的研究。如此复杂的方法需要开展训练有素的研究 具有多学科“心态”的科学家：对跨学科工作的热情和欣赏 对老问题获得新的视角并制定创新的解决方案。然而，开发管道 这些研究人员不足以应对重点人群日益增长的癌症负担和癌症风险。 拟议的中共博士后研究培训计划的总体目标是启动 新一代临床和非临床研究人员准备将这种多学科方法应用于 CPC 针对重点人群的研究。该计划的目标是： 1) 提供量身定制的课程 将生物学、医学、流行病学、行为和社区观点纳入 CPC 研究 优先人群； 2）促进CPC研究的跨学科方法； 3）培养多学科 通过指导研究，学员可以在 CPC 中开展研究职业。为了成功实现这些目标， 计划将招募有潜力成为未来多学科 CPC 调查员的候选人；提供 出色的指导；培养多学科团队的科学环境；并促进实现 作为独立研究者追求和维持长期成功所需的学术生涯和生活技能。 该项目的优势在于西奈山多样化的 CPC 研究组合、其与 新近获得 NCI 认证的蒂施癌症研究所 (Tisch Cancer Institute)，该研究所是一个方法论多样化且成就卓著的网络 导师，以及西奈山为社会经济、种族和民族多元化提供服务的悠久历史 组成其集水区的社区。它以我们之前非常成功的 R25T 行为模型为蓝本 中国共产党培训计划。该计划每年将录取 2 名候选人参加为期 2 年的奖学金，培训一名 5年内总共有10名新调查员。每位学员将在协商中制定高度定制的课程 与他们的导师和项目总监。课程将植根于所需的 11 项核心能力 在针对优先人群的多学科 CPC 研究中开始成功的职业生涯。学员将拥有 主要和次要导师，他们的进展将由导师委员会仔细监控。 该计划将接受内部和外部专家顾问委员会的指导，其绩效将 通过选定的指标进行定期监控，以确保持续改进、增长和可持续性。