Mentoring Research Excellence in Aging and Regenerative Medicine

指导衰老和再生医学领域的卓越研究

基本信息

批准号：
8883599
负责人：
S MICHAL JAZWINSKI
金额：
$ 206.62万
依托单位：
TULANE UNIVERSITY OF LOUISIANA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-01 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8883599
关键词：
Achievement Activities of Daily Living Administrator Advisory Committees Aging Applications Grants Area Behavioral Biology of Aging Biomedical Engineering Biomedical Research Biometry Businesses Cardiovascular system Cell Aging Cells Centers of Research Excellence Clinical Collaborations Communities Community Health Core Facility Cultured Cells Data Analyses Degenerative Disorder Development Environment Epidemiologist Epigenetic Process Evaluation Experimental Designs Exposure to Faculty Fostering Foundations Fruit Funding Genetic Genomics Geriatrics Gerontology Goals Government Grant Growth Growth and Development function Health Health Sciences Health system Human Human Resources Individual Interdisciplinary Study Laboratories Lawyers Leadership Life Life Expectancy Louisiana Measures Medicine Mentors Molecular National Institute on Aging Neurocognitive Neurosciences Peer Review Physical Function Positioning Attribute Preventive Process Quality of life Records Regenerative Medicine Research Research Infrastructure Research Personnel Resources Retirement Rodent Model Schools Scientist Seasons Secure Series Services Social Workers Source Speed Structure Time Training Translating Translational Research United States National Institutes of Health Universities Update Writing age related aging population base career career development cell age clinical practice cognitive function collaborative environment design expectation experience healthy aging interdisciplinary approach interest loss of function medical schools meetings member multidisciplinary programs social sound success

项目摘要

DESCRIPTION (provided by applicant): The objective of this COBRE application is to develop the careers of promising junior investigators in biomedical aging research and to build programmatic strength in this area. Career development will utilize a strong core of research mentors who will provide career development advice as well as sound practical advice on scientific development and laboratory management. The five projects in this COBRE focus on several complementary themes that contribute to our understanding of aging, from basic genetic and epigenetic contributions through cardiovascular and neurocognitive mechanisms. Three of the projects feature human aging, one focuses on rodent models, and one utilizes cultured cells. All of the projects have a high translational relevance. An internal advisory committee consisting of seasoned scientist/administrators has been appointed. The COBRE leadership is composed of mentors and core senior investigators for this COBRE, and they are strongly committed to the program; these scientists have outstanding research and mentoring records. In addition, a prominent board of external advisors with outstanding research careers and track records of career development for junior scientists will participate in both the guidance and evaluation of the progress of the junior investigators and of the COBRE program itself. Career development will involve a series of program meetings, exposure to didactic grant-writing sessions, and seminars to develop a highly collaborative environment for both the junior faculty, as well as other members of the Tulane Center for Aging. The COBRE also provides a Biostatistics and Genomics Research Core facility for our scientists to make new experimental possibilities available to them and to enhance experimental design and data analysis. The Tulane Center for Aging provides an outstanding interdisciplinary environment for aging research involving eight of the schools at Tulane University. The Center enjoys strong institutional support for its development and growth. This COBRE will represent the centerpiece of the Tulane Center for Aging, and it will contribute strongly to our building of an exceptional biomedical aging research enterprise in Louisiana.

描述（由申请人提供）：该毛病申请的目的是发展有前途的生物医学衰老研究中有前途的初级研究人员的职业，并在该领域建立程序化实力。职业发展将利用强大的研究导师核心，他们将为科学发展和实验室管理提供职业发展建议以及合理的实用建议。这个鞋垫中的五个项目集中于几个互补主题，这些主题有助于我们对衰老的理解，从基本的遗传和表观遗传学贡献通过心血管和神经认知机制。其中三个项目具有人类衰老，一个项目专注于啮齿动物模型，一个项目利用了培养的细胞。所有项目都具有很高的转化相关性。已任命了由经验丰富的科学家/管理员组成的内部咨询委员会。毛绒领导层由这只毛病的导师和核心高级调查员组成，他们强烈致力于该计划。这些科学家拥有出色的研究和指导记录。此外，具有出色的研究职业和初级科学家职业发展记录的著名外部顾问委员会将参与初级调查员和Cobre计划本身的进度的指导和评估。职业发展将涉及一系列的计划会议，接触教学赠款写作会议以及为初级教师以及图兰衰老中心的其他成员开发高度协作环境的研讨会。该鞋底还为我们的科学家提供了生物统计学和基因组学研究核心设施，以使他们可以使用新的实验可能性并增强实验设计和数据分析。杜兰（Tulane）老龄化中心为涉及杜兰大学（Tulane University）的八所学校的衰老研究提供了一个杰出的跨学科环境。该中心为其发展和增长提供了强有力的机构支持。这块鞋底将代表杜兰衰老中心的核心，它将为我们在路易斯安那州建立非凡的生物医学衰老研究企业做出巨大贡献。