Active Distributed Electrode Array Network for Electrical Stimulation Therapy

用于电刺激治疗的有源分布式电极阵列网络

• 批准号: 8199338
• 负责人: Eric C Hartman
• 金额: $ 49.45万
• 依托单位: CUSTOMKYNETICS, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8199338
• 关键词: Address; Area; Characteristics; Clinic; Clinical; Clinical Research; Computer Architectures; Computer software; Data; Delaware; Development; Devices; Doctor of Philosophy; Electric Stimulation; Electrodes; Electromagnetics; Environment; Evaluation; Generic Drugs; Goals; Government; Human; Industry; Knowledge; Lead; Maintenance; Marketing; Muscle; Orthotic Devices; Performance; Phase; Physiologic pulse; Price; Progress Reports; Public Health; Regimen; Rehabilitation Research; Rehabilitation therapy; Research; Research Personnel; Risk Management; Small Business Innovation Research Grant; Spinal cord injury; System; Technology; Testing; Therapeutic Intervention; Transcutaneous Electric Nerve Stimulation; Universities; Work; clinical application; clinical efficacy; commercial application; commercialization; cost; design; empowered; experience; improved; interest; meetings; novel; programs; prototype; research and development; research study; technology/technique; tool

DESCRIPTION (provided by applicant): Transcutaneous electrical stimulation applications involving high numbers of stimulated muscles have been an area of growing interest in recent years. customKYnetics has been approached by research groups and stimulation application developers requesting high channel count stimulation devices for use in their spinal cord injury rehabilitation research studies and products. Existing devices do not offer the features and/or number of stimulation channels required for these applications. Such high channel count devices are often cost prohibitive due to the size and complexity of the stimulator and the limited market for any particular configuration. Devices that are available lack the technological capability to coordinate the activity of the electrode pairs in an application-specific manner. Such applications have also lacked clinical acceptance because managing the large number of wires has been burdensome and impractical. We propose Active Distributed Electrode Array (ADEA) technology, which offers two novel features that address these problems: network architecture and end-user programmability. With these features, the ADEA system will be fully configurable (both in hardware and software) by the application developer (i.e., researcher, specialized clinician, or OEM company) to create application-specific stimulation/sensing networks and stimulation regimens. No end-user programming experience will be required. We successfully completed Phase I work, including feasibility demonstration of the node concept. The goals of this Phase II SBIR project will be to develop clinically viable stimulation and sensing nodes, an ADEA stimulator/controller module, and an end-user programming suite, and to demonstrate efficacy of the technology. The target markets for this device will be specialized clinics, research groups, and OEM companies. The target price for the system will be $3000 in volume for an 8-channel configuration (OEM market). PUBLIC HEALTH RELEVANCE: The proposed work may benefit public health through development of a clinically viable electrical stimulation technology for use in myriad rehabilitation applications. Compared to existing devices and techniques, the technology may improve efficacy, availability, ease of use, and reduce cost of the therapeutic interventions requiring high numbers of muscles to be activated using electrical stimulation in a well controlled/coordinated fashion.

描述（由申请人提供）：涉及大量受刺激肌肉的经皮电刺激应用近年来已成为人们日益感兴趣的领域。研究小组和刺激应用开发商已与 customKYnetics 接洽，要求将高通道数刺激设备用于他们的脊髓损伤康复研究和产品。现有设备不提供这些应用所需的功能和/或刺激通道数量。由于刺激器的尺寸和复杂性以及任何特定配置的有限市场，这种高通道数设备的成本通常过高。现有的设备缺乏以特定于应用的方式协调电极对的活动的技术能力。此类应用还缺乏临床接受度，因为管理大量电线既繁重又不切实际。我们提出了有源分布式电极阵列（ADEA）技术，该技术提供了解决这些问题的两个新颖功能：网络架构和最终用户可编程性。凭借这些功能，应用程序开发人员（即研究人员、专业临床医生或 OEM 公司）可以完全配置 ADEA 系统（硬件和软件），以创建特定于应用程序的刺激/传感网络和刺激方案。不需要最终用户编程经验。我们成功完成了第一阶段工作，包括节点概念的可行性论证。该第二阶段 SBIR 项目的目标是开发临床上可行的刺激和传感节点、ADEA 刺激器/控制器模块和最终用户编程套件，并展示该技术的功效。该设备的目标市场将是专业诊所、研究小组和 OEM 公司。 8 通道配置系统的目标批量价格为 3000 美元（OEM 市场）。 公共健康相关性：拟议的工作可能通过开发临床上可行的电刺激技术用于多种康复应用而有益于公共健康。与现有的设备和技术相比，该技术可以提高功效、可用性、易用性，并降低需要使用电刺激以良好控制/协调的方式激活大量肌肉的治疗干预的成本。