Production Assistance for Cellular Therapies (PACT)- Cell Processing Facilities Cell manufacturing and process development services for PCT0031-02: GMP Production of iPSC Line and Scale-up of Cardiac

细胞疗法生产协助 (PACT) - 细胞加工设施 PCT0031-02 的细胞制造和工艺开发服务：iPSC 生产线的 GMP 生产和心脏的放大

• 批准号: 10090766
• 负责人: Joshua M Hare
• 金额: $ 101.72万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-12-10 至 2021-08-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10090766
• 关键词: Cardiac; Cardiac development; Cell Differentiation process; Cell Line; Cell Therapy; Cells; Clinical; Fibroblasts; Hares; Human; National Heart, Lung, and Blood Institute; Peer Review; Production; Protocols documentation; Resources; Services; United States National Institutes of Health; cell bank; exosome; induced pluripotent stem cell; manufacturing process development; programs; scale up; stem cells

The purpose of this task order to provide cell manufacturing services to an approved PACT program requestor. Dr. Hare's CPF will provide clinical grade Cardiac progenitor cells and exosomes to the requestor, Dr. Ashraf. The project has undergone scientific merit review by an external, peer review board and administrative review by NHLBI PACT project/program officers.

此任务订单的目的是向经批准的 PACT 计划请求者提供电池制造服务。 Hare 博士的 CPF 将为请求者 Ashraf 博士提供临床级心脏祖细胞和外泌体。该项目已经过外部同行评审委员会的科学价值评审和 NHLBI PACT 项目/计划官员的行政评审。