Integrating a combination HIV prevention intervention into a widely-used geosocial app for Chinese MSM

将艾滋病毒预防综合干预措施纳入中国 MSM 广泛使用的地理社交应用程序中

基本信息

批准号：
10079463
负责人：
Aaron Julius Siegler
金额：
$ 61.64万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-01-23 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10079463
关键词：
AIDS prevention AIDS/HIV problem Appointment Behavioral Biological Factors Books Canada Caring China Chinese People Cities Clinic Cross-Sectional Studies Custom Data Data Collection Detection Development Diagnosis Diagnostic Reagent Kits Epidemic Event Exercise Exposure to Focus Groups HIV HIV diagnosis HIV/STD Health Hearing Home Home Care Services Human immunodeficiency virus test Incidence India Individual Intervention Intervention Studies Lubricants Mexico Modeling NIH Office of AIDS Research Nongovernmental Organizations Participant Patients Persons Pilot Projects Population Prevention Process Public Health Research Research Priority Resources Review Literature Risk Schedule Service delivery model Services Sexual Health Strategic Planning Structure Surveys System Testing Time Treatment Efficacy Trust United States Work acceptability and feasibility base cognitive interview cohort condomless anal sex condoms design efficacy study experience high risk home based service home test interest mathematical model meetings men who have sex with men novel pre-exposure prophylaxis prevention service preventive intervention programs public health intervention recruit satisfaction scale up self testing service delivery service intervention service uptake smartphone Application successful intervention tool transmission process

项目摘要

PROJECT SUMMARY/ABSTRACT A number of HIV prevention interventions are known to be effective: HIV testing and linkage to care as appropriate, condom use, and HIV pre-exposure prophylaxis (PrEP). Unfortunately, achieving sufficient use of these prevention services has been challenging. In China, men who have sex with men (MSM) are the only risk group with increasing HIV case detection, representing 26% of new cases diagnosed in 2014. One way to obtain increased prevention intervention use would be to help individuals understand when they should be using certain prevention services, and to make accessing services less burdensome. The proposed research will involve conducting a literature review and developing mathematical models to explore different scenarios of providing a combination HIV prevention service intervention for MSM in China. Using information from this exercise, we will develop and pilot test a combination HIV intervention built into a smartphone app. The intervention will include home care services such as home HIV self-testing and home ordering of prevention products such as condoms. If the intervention proves to be feasible and acceptable, the pilot test will facilitate design of a larger study of intervention efficacy. The intervention will be built into an existing, widely-accessed geosocial networking app used by MSM. By building the intervention into a platform already used by millions of individuals, we anticipate that, in the event that the intervention is demonstrated to be efficacious, scale-up of the intervention will be readily achievable. The proposed research seeks to develop mathematical models and an intervention that would reduce the incidence of HIV/AIDS, meeting an overarching research priority identified in the Strategic Plan of the NIH Office of AIDS Research.

项目概要/摘要已知许多艾滋病毒预防干预措施是有效的：艾滋病毒检测和与护理的联系适当的、使用安全套和 HIV 暴露前预防 (PrEP)。不幸的是，实现充分利用这些预防服务一直具有挑战性。在中国，男男性行为者（MSM）是唯一 HIV 病例检出率不断上升，占 2014 年新诊断病例的 26%。一种方法获得更多的预防干预措施的使用将有助于个人了解何时应该采取预防措施使用某些预防服务，并减轻获取服务的负担。拟议的研究将涉及进行文献综述并开发数学模型来探索不同的场景为中国的男男性行为者提供艾滋病毒综合预防服务干预。使用来自此的信息在练习中，我们将开发并试点测试内置于智能手机应用程序中的艾滋病毒综合干预措施。这干预措施将包括家庭护理服务，例如家庭艾滋病毒自我检测和家庭预防订购避孕套等产品。如果干预措施被证明是可行和可接受的，试点测试将有助于设计更大规模的干预效果研究。该干预措施将被纳入现有的、广泛使用的 MSM 使用的地理社交网络应用程序。通过将干预措施构建到已被数百万人使用的平台中个人，我们预计，如果干预措施被证明是有效的，那么我们将扩大干预是很容易实现的。拟议的研究旨在开发数学模型和减少艾滋病毒/艾滋病发病率的干预措施，满足总体研究优先事项 NIH 艾滋病研究办公室的战略计划中确定了这一点。