Examining the long-term relationship between sleep and diet

检查睡眠和饮食之间的长期关系

• 批准号: 10082299
• 负责人: Kaitlin Storck Potts
• 金额: $ 4.6万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10082299
• 关键词: Accounting; Address; Adult; Affect; African American; Alabama; American; Area; Body mass index; Cardiometabolic Disease; Cardiovascular Diseases; Cause of Death; Characteristics; Childhood; Chronic; Chronic Disease; Cohort Studies; Communities; Complex; Data; Development; Diabetes Mellitus; Diet; Dietary intake; Disease; Drowsiness; Epidemiology; Faculty; Food; Foundations; Future; Goals; Health; Heart; Hypertension; Intervention; Knowledge; Lead; Life; Life Cycle Stages; Life Style; Link; Longitudinal Studies; Louisiana; Mentors; Methods; Mississippi; Modification; Morbidity - disease rate; Nutritional; Obesity; Outcome; Performance; Personal Satisfaction; Physical activity; Play; Population; Population Heterogeneity; Prevalence; Race; Research; Research Personnel; Research Project Grants; Research Training; Risk; Risk Factors; Role; Rural Community; Sex Differences; Sleep; Sleep Apnea Syndromes; Sleep Deprivation; Sleep Disorders; Sleep disturbances; Socioeconomic Status; Stratification; Techniques; Time; Unhealthy Diet; United States; United States National Institutes of Health; Weight Gain; Woman; Work; biological sex; biracial; black women; cardiometabolic risk; cardiovascular risk factor; career; cohort; design; dietary; disease disparity; experience; experimental study; falls; health disparity; healthy weight; improved; lipid disorder; low socioeconomic status; meetings; men; middle age; mortality; obesity prevention; prevent; programs; prospective; racial difference; sex; skills; sleep behavior; sleep health; sleep pattern; sleep quality; young adult

PROJECT SUMMARY/ABSTRACT Poor diet quality contributes to the excess burden of cardiometabolic diseases among U.S. adults. Short sleep and poor quality sleep are increasing and have been linked to obesity and cardiometabolic diseases. There is evidence that both diet and reduced sleep duration and quality impact African Americans and those with low socio-economic status more so than other groups, and that these differences may contribute to health disparities in cardiometabolic diseases. Specific aspects of diet have been linked to sleep outcomes in the short term and similarly, experimental studies of sleep restriction have found short sleep can lead to poor dietary choices and weight gain, demonstrating the bi-directionality of the diet and sleep relationship in the near term. However, the inter-relationship between diet and sleep is complex and has rarely been studied in the long-term nor with aspects of sleep beyond duration including quality, regularity, disturbance, and sleepiness. Therefor, this study will address this knowledge gap by examining the long-term relationships between diet and sleep in the Bogalusa Heart Study cohort of 1250 men and women from a biracial community in Louisiana that have been prospectively followed for over 40 years, since childhood. The first aim of the research is to prospectively examine the effect of multiple aspects of sleep (e.g. duration, quality, sleepiness) on dietary intake in midlife among the Bogalusa Heart Study cohort. The second aim of the research is to prospectively examine the effect of dietary intake in young adulthood on long-term sleep outcomes later in life including sleep duration, quality, regularity, disturbance, and sleepiness accounting for body mass index, risk for sleep disordered breathing, and physical activity. The third aim is to determine if differences by race, biologic sex, and socioeconomic status exist in the relationships between diet and sleep over the life course. The long-term goal in pursuing this research project and training plan is to produce an independent investigator in nutritional and lifestyle epidemiology, well prepared to pursue a research career that alleviates the burden of disparity in obesity and obesity-related morbidity and mortality for people in the Gulf South Region of the United States. This will be achieved by meeting the overall objective of this project, implementing a tailored, individualized, mentored research training experience that contributes to closing a long-standing knowledge gap in the long-term relationship between diet and sleep. The impact of this work will be to produce a future leader in nutritional and lifestyle epidemiology. The knowledge gained will allow for the development of appropriately timed and targeted intervention opportunities to maintain healthy weight and sleep patterns that prevent chronic cardiometabolic diseases among diverse populations in the U.S. while reducing health disparities. The Bogalusa Heart Study cohort is a unique and ideal setting in which to perform this research.

项目概要/摘要 不良的饮食质量导致美国成年人心脏代谢疾病的负担过重。睡眠时间短 睡眠质量差的情况正在增加，并且与肥胖和心脏代谢疾病有关。有 有证据表明，饮食和睡眠时间和质量的减少都会影响非裔美国人和睡眠质量低下的人 社会经济地位高于其他群体，这些差异可能有助于健康 心脏代谢疾病的差异。饮食的特定方面与睡眠结果有关 短期内，类似地，睡眠限制的实验研究发现睡眠不足会导致睡眠质量不佳 饮食选择和体重增加，证明了饮食和睡眠关系的双向性 近期。然而，饮食和睡眠之间的相互关系很复杂，并且很少被研究。 长期或超出持续时间的睡眠方面，包括质量、规律性、干扰和 困倦。因此，本研究将通过考察长期关系来解决这一知识差距 Bogalusa 心脏研究队列中来自混血儿社区的 1250 名男性和女性的饮食和睡眠之间的关系 在路易斯安那州，从童年起就被前瞻性地跟踪了 40 多年。该项目的第一个目标是 研究旨在前瞻性地研究睡眠多个方面的影响（例如持续时间、质量、困倦） Bogalusa 心脏研究队列中的中年饮食摄入量。研究的第二个目的是 前瞻性研究青年时期的饮食摄入对晚年长期睡眠结果的影响 包括睡眠持续时间、质量、规律性、干扰和嗜睡（与体重指数、风险相关） 用于睡眠呼吸障碍和体力活动。第三个目标是确定种族差异是否存在， 生物性别和社会经济地位存在于生命历程中饮食和睡眠之间的关系中。 开展该研究项目和培训计划的长期目标是培养一名独立研究者 在营养和生活方式流行病学领域，为从事减轻负担的研究事业做好了充分准备 海湾南部地区人群肥胖以及与肥胖相关的发病率和死亡率的差异 美国。这将通过满足该项目的总体目标、实施量身定制的、 个性化的、有指导的研究培训经验，有助于总结长期存在的知识 饮食和睡眠之间的长期关系存在差距。这项工作的影响将是创造一个未来 营养和生活方式流行病学的领导者。所获得的知识将有助于发展 适当时机和有针对性的干预机会，以保持健康的体重和睡眠模式， 预防美国不同人群的慢性心脏代谢疾病，同时降低健康水平 差异。 Bogalusa 心脏研究队列是进行这项研究的独特而理想的环境。