ANTERIOR CINGULATE DEFICITS IN OBSESSIVE-COMPULSIVE DISORDER

强迫症中的前扣带肌缺陷

• 批准号: 8167289
• 负责人: Patricia A. Gruner
• 金额: $ 0.42万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167289
• 关键词: Anterior; Base of the Brain; Childhood; Computer Retrieval of Information on Scientific Projects Database; DNA; Diffusion Magnetic Resonance Imaging; Disease; Functional Magnetic Resonance Imaging; Funding; Genetic; Grant; Institution; Neurobiology; Obsessive-Compulsive Disorder; Patients; Play; Research; Research Personnel; Resources; Role; Source; United States National Institutes of Health; endophenotype; healthy volunteer; improved

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The current study will utilize diffusion tensor imaging and functional magnetic resonance imaging to investigate the anterior cingulate in 40 pediatric patients with obsessive compulsive disorder (OCD) and 40 healthy volunteers. Subjects will also provide DNA to investigate the genetic basis of brain abnormalites in OCD. We hope to improve our understanding of the role that the anterior cingulate plays in the neurobiology of OCD and whether abnormalities in this region can serve as endophenotypes in genetic studies of the disorder.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 目前的研究将利用弥散张量成像和功能磁共振成像来研究 40 名患有强迫症 (OCD) 的儿科患者和 40 名健康志愿者的前扣带回。 受试者还将提供 DNA 来研究强迫症大脑异常的遗传基础。 我们希望加深对前扣带回在强迫症神经生物学中所起作用的理解，以及该区域的异常是否可以作为该疾病的遗传研究中的内表型。