Examining the Effect of Behavioral Activation on Substance Use Outcomes

检查行为激活对药物使用结果的影响

基本信息

批准号：
8064350
负责人：
Jessica F Magidson
金额：
$ 4.26万
依托单位：
UNIV OF MARYLAND, COLLEGE PARK
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-04-15 至 2013-04-14
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8064350
关键词：
Abnormal coordination Accounting Address Affect African American Aftercare Alcohol or Other Drugs use Area Behavioral Clinical Complex Contracts Control Groups Counseling Data Daughter Depressed mood Disease remission District of Columbia Dropout Drops Drug Rehabilitation Centers Drug user Elements Event Frequencies Future Goals Health Personnel Illicit Drugs Individual Intervention Investigation Life Link Low income Major Depressive Disorder Manuals Measures Mediating Mediator of activation protein Mental Depression Minority Modeling Motivation Nature Outcome Patient Self-Report Patients Pilot Projects Population Population Intervention Positive Reinforcements Poverty Psychological reinforcement Public Health Relapse Residential Treatment Rewards Sample Size Sampling Staging Testing Theoretical model Time Treatment outcome Work base career clinically significant depressive symptoms environmental change ethnic minority population inner city meetings novel psychosocial skills substance abuse treatment theories treatment as usual

项目摘要

DESCRIPTION (provided by applicant): Major depressive disorder (MDD) is highly prevalent among substance users, which has significant clinical and public health implications, including poor substance use treatment outcomes. Rates of substance use and depression have been shown to disproportionately affect ethnic minorities in inner-city areas; yet unfortunately, few interventions targeting depression have been developed to meet the specific needs of depressed, minority substance users living in the inner-city. One approach that has been suggested to be useful in this context is behavioral activation (BA), which treats depression by increasing individuals' engagement in pleasant events, and thus increasing positive reinforcement (Jacobson et al., 1996; Lejuez et al., 2001). Daughters and colleagues (2008) have adapted BA to meet the specific needs of inner-city, African American substance users with depression, and in a preliminary pilot study for this treatment [Life Enhancement Treatment for Substance Use (LET'S ACT)], LET'S ACT was associated with a significant reduction in self-reported depressive symptoms and a significant increase in enjoyment and reward value of activities. While preliminary findings for LET'S ACT prove promising, several extensions of the previous study are necessary, including 1) assessment of post-treatment substance use relapse 2) utilization of a contact time-matched control treatment, and 3) the use of a larger sample size to allow for more complex analyses of the mechanisms underlying treatment outcomes. Thus, the current study will address these limitations by comparing LETS ACT to Supportive Counseling (SC) among a sample of 196 low-income substance users with MDD receiving residential substance abuse treatment in inner-city Washington, DC. Depression is prevalent in substance using populations and is associated with poor substance use treatment outcomes, yet few interventions have been developed to treat depression among inner-city, minority illicit drug users. This proposal aims to further develop a behavioral activation treatment for depression specifically for inner-city illicit drug users in residential substance use treatment and examine its effect on substance use treatment dropout and post-treatment relapse.

描述（由申请人提供）：主要抑郁症（MDD）在药物使用者中非常普遍，这具有重大的临床和公共卫生影响，包括药物使用治疗结果不良。已经证明，药物使用和抑郁症的速度不成比例地影响少数民族的城市地区；然而，不幸的是，很少有针对抑郁症的干预措施来满足居住在城市中心的沮丧，少数族裔用户的特定需求。在这种情况下，一种被认为是有用的方法是行为激活（BA），该方法通过增加个人参与愉快事件并从而增加积极强化来治疗抑郁症（Jacobson等，1996; Lejuez等，2001）。女儿和同事（2008年）已经改编了学士学位，以满足城市内，非洲裔美国药物使用者的特定需求，并且在对这种治疗的初步试点研究中[使用寿命增强药物的治疗方法（让我们ACT）]，让我们的行为与自我报告的抑郁症状症状大幅减少相关，并大大减少了享受和奖励价值的增长和奖励价值。尽管我们的ACT的初步发现证明了有前途的结果，但必须进行以前的研究的几项扩展，包括1）评估治疗后物质使用复发2）利用接触时间匹配的控制治疗方法，以及3）使用更大的样本量以允许对治疗治疗机制进行更复杂的分析。因此，当前的研究将通过将LES LES ACT与支持性咨询（SC）进行比较，在196个低收入药物使用者中，MDD在华盛顿特区内城接受住宅药物滥用治疗的样本中。抑郁症在使用种群的物质中普遍存在，并且与药物使用治疗结果不佳有关，但几乎没有采取干预措施来治疗少数族裔非法吸毒者之间的抑郁症。该提案旨在进一步开发针对抑郁症的行为激活治疗，专门针对内城非法吸毒者在住宅药物使用治疗中，并检查其对药物使用治疗辍学和治疗后复发的影响。